Fibrate

Effects Fibrates (ATC C10AB) have lipid-lowering properties. They primarily lower elevated blood triglyceride levels and have a moderate effect on LDL cholesterol and slightly increase HDL. The effects are due to activation of nuclear receptors PPAR (mainly PPARα). Indications Blood lipid disorders, especially hypertriglyceridemia. Agents Bezafibrate (Cedur retard) Fenofibrate (Lipanthyl) Fenofibric acid (Trilipix) Gemfibrozil (Gevilon) … Fibrate

Ciprofibrate

Products Ciprofibrate was commercially available in many countries in capsule form (Hyperlipen, off label). It was approved in 1993 and has not been available since 2013. Structure and properties Ciprofibrate (C13H14Cl2O3, Mr = 289.2 g/mol) is a racemate and a phenoxyisobutyric acid derivative. It exists as a white to pale yellow powder that is practically … Ciprofibrate