Products Ifosfamide is commercially available as a dry substance for intravenous infusion (Holoxan). It has been approved in many countries since 1979. Structure and properties Ifosfamide (C7H15Cl2N2O2P, Mr = 261.1 g/mol) is an oxazaphosphorine and nitrogen-lost derivative, and an analog of cyclophosphamide. Ifosfamide is a racemate and exists as a white, crystalline, hygroscopic powder that … Ifosfamide
Lupus nephritis is an inflammation of the kidneys caused by systemic lupus erythematosus (SLE). SLE, in turn, is an autoimmune disease that, in addition to affecting the skin, can also affect various organs or regions of the body. Thus, in patients suffering from lupus nephritis, the kidneys are affected. What is lupus nephritis? About 70 … Lupus Nephritis: Causes, Symptoms & Treatment
Hand-foot syndrome occurs more frequently during treatment with cytostatic drugs. Patients’ feet and hands become red, scaly, and painful or are affected by sensory disturbances. Hand-foot syndrome is treated symptomatically with analgesics and creams. What is hand-foot syndrome? Therapeutic drug treatments are usually associated with various side effects and health risks. In particular, phenomena such … Hand-foot Syndrome: Causes, Symptoms & Treatment
Bladder pain is also known as urinary bladder pain or cystodynia. Most often, the pain occurs as a result of inflammation and irritation in the bladder wall area. Bladder pain can be acute or chronic. What is bladder pain? Bladder pain often occurs in the setting of a urinary tract infection, such as cystitis. Bladder … Bladder Pain: Causes, Treatment & Help
Rituximab is a drug in the cytostatic drug class. It is a monoclonal antibody used primarily in the treatment of malignant lymphoma. What is rituximab? Rituximab was developed in the 1990s by Lee Nadler at Dana-Farber Cancer Institute. It was the first antibody approved for the treatment of cancer worldwide. In the EU, rituximab is … Rituximab: Effects, Uses & Risks
In microscopic polyangiitis, blood vessels become inflamed by autoimmunologic processes. The cause is not yet known but is speculatively associated with immunologic misprogramming after infection. The prognosis for untreated patients is unfavorable, but drug-treated patients do not necessarily have an unfavorable course. What is microscopic polyangiitis? Microscopic polyangitis corresponds to polyarteritis nodosa, also known as … Microscopic Polyangiitis: Causes, Symptoms & Treatment
Cryoglobulinemia is a disease belonging to the group of vascular inflammations (vasculitides). In most cases, chronic hepatitis C underlies the inflammation. What is cryoglobulinemia? Cryoglobulinemia is a vasculitis, or inflammation of the blood vessels. This inflammation is triggered by the deposition of immune complexes or immunoglobulins in the small blood vessels. These immunoglobulins are called … Cryoglobulinemia: Causes, Symptoms & Treatment
Pentostatin is a pharmaceutical agent that belongs to the antimetabolites and is used in the treatment of hairy cell leukemia. Hairy cell leukemia is characterized by an abnormality of lymphocytes and is characterized by a decrease in white and red blood cells and anemia, among other symptoms. What is pentostatin? Pentostatin is used in the … Pentostatin: Effects, Uses & Risks
Pyoderma gangraenosum is characterized by ulceration of the skin and formation of skin necrosis. In most cases, it is not a disease in its own right, but a symptom of another underlying disorder. In severe cases, entire sections of skin tissue die. What is pyoderma gangraenosum? Pyoderma gangraenosum is characterized by ulceration and the death … Pyoderma Gangraenosum: Causes, Symptoms & Treatment
Autoimmune hemolytic anemia is a specific form of anemia that is acquired rather than congenital. The condition is also referred to in medical parlance by the abbreviation AIHA. The disease is triggered by certain antibodies directed against the body’s own antigens. The antibodies bind primarily to the red blood cells (scientific term erythrocytes) and in … Autoimmune Hemolytic Anemia: Causes, Symptoms & Treatment
Chronic inflammatory demyelinating polyneuropathy is also known as chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). It is a very rare disease of the peripheral nerves. What is chronic inflammatory demyelinating polyneuropathy? Chronic inflammatory demyelinating polyneuropathy is a disease of the nerves located outside the central nervous system. The disease is rare, with an incidence of two per … Chronic Inflammatory Demyelinating Polyneuropathy: Causes, Symptoms & Treatment
Erdheim-Chester disease is a so-called non-Langerhans type of histiocytosis. This is a multisystem disease that is associated, for example, with skeletal complaints or pain in the bones or also diabetes insipidus. In addition, damage to the kidneys as well as the central nervous system in conjunction with cardiovascular symptoms is possible. Erdheim-Chester disease is often … Erdheim-Chester Disease: Causes, Symptoms & Treatment