Products Ondansetron is commercially available in the form of film-coated tablets, meltable tablets (lingual tablets), as a syrup, and as an infusion/injection preparation. In addition to the original Zofran, generic versions are also available. Ondansetron was introduced in 1991 as the first active ingredient from the group of 5-HT3 receptor antagonists was approved. Structure and … Ondansetron
Products Febuxostat is commercially available in the form of film-coated tablets (Adenuric). It was approved in many countries in 2016. It was registered in the EU in 2008 and in the US in 2009 (US: Uloric). Structure and properties Febuxostat (C16H16N2O3S, Mr = 316.4 g/mol), unlike allopurinol, does not have a purine structure. It is … Febuxostat
Products Hemp and preparations made from it, such as marijuana, cannabis resin, THC, and cannabis extracts, are generally among the prohibited narcotics in many countries. However, the Federal Office of Public Health may grant exemptions for research, drug development and limited medical use. In 2013, a cannabis oral spray (Sativex) was approved as a medicine … Cannabis
Products The cannabis oral spray Sativex was approved in many countries in 2013. It is subject to narcotics legislation and requires an enhanced prescription. In Germany, Sativex has been available since 2011. Structure and properties The oral spray contains a thick extract of the hemp plant L., which is extracted from the leaves and flowers … Cannabis Mouth Spray
Products Androgens are commercially available as oral tablets and capsules, transdermal gels and transdermal patches, and injectables, among others. Testosterone was first isolated in the 1930s. Structure and properties Androgens generally have a steroidal structure and are related to testosterone. They are steroid hormones that are often present as esters in drugs. Effects Androgens (ATC … Androgens: Steroid Hormones
Products Rotigotine is commercially available as a transdermal patch in various potencies (Neupro). It was approved in many countries in 2006 as the first TTS for Parkinson’s disease therapy. Structure and properties Rotigotine (C19H25NOS, Mr = 315.5 g/mol) is an aminotetralin and thiophene derivative structurally related to dopamine. It has a non-ergoline structure and exists … Rotigotine
Products Dopamine agonists are commercially available in the form of tablets, sustained-release tablets, transdermal patches, and injectables, among others. Structure and properties The first active ingredients, such as bromocriptine (Figure), were derived from ergot alkaloids. These are referred to as ergoline dopamine agonists. Later, agents with a nonergoline structure, such as pramipexole, were also developed. … Dopamine Agonists
Products Vortioxetine is commercially available as film-coated tablets and as an oral solution (drops). It was approved in the United States and the EU in 2013 and in many countries in 2016 (Brintellix, United States: Trintellix). Structure and properties Vortioxetine (C18H22N2S, Mr = 298.4 g/mol) is a piperazine derivative. It is present in the film-coated … Vortioxetine
Products Testosterone is commercially available as a drug product including transdermal gel, transdermal patch, transdermal solution, and injectable. In some countries, other dosage forms such as buccal tablets are available. Andriol Testocaps capsules have been discontinued in many countries since 2020. Structure and properties Testosterone (C19H28O2, Mr = 288.4 g/mol) is a steroid. It exists … Testosterone Effects
