Production Anhydrous sodium sulfate (250) 42.0 g Sodium hydrogen carbonate (250) 36.3 g Sodium chloride (250) 18.4 g Potassium sulfate (250) 3.3 g The salts are mixed. Effects Laxative Indications For short-term use in constipation Dosage 1-2 teaspoons to 1 glass of water Precautions See under sodium sulfate
Products Carteolol is available in the form of extended-release eye drops (Arteoptic LA). Carteolol has been approved in many countries since 1984. Arteopilo, the combination with pilocarpine, is no longer marketed in many countries. Structure and properties Carteolol (C16H24N2O3, Mr = 292.4 g/mol) is a dihydroquinolinone and a racemate. It is present in drugs as … Carteolol
Products Medicines containing colchicine are no longer on the market in many countries. Drugs are available abroad that can be imported. It may also be possible to prepare an extemporaneous formulation in a pharmacy (difficulties: toxicity, substance). Stem plant Colchicine is the main alkaloid of the autumn crocus (Colchicaceae), which contains it particularly abundantly in … Colchicine
Products Octreotide is commercially available as an injectable (Sandostatin, Sandostatin LAR, generics). It has been approved in many countries since 1988. Structure and properties Octreotide is a synthetic octapeptide derivative of the hormone somatostatin. It is present in the drug as octreotide acetate and has the following structure: D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol, xCH3COOH (x = 1.4 to 2.5). … Octreotide
1. symptom treatment Beta2-sympathomimetics are derived from epinephrine. They selectively stimulate the adrenergic β2-receptors of bronchial muscles and thus have a bronchospasmolytic effect. For rapid symptom relief, fast-acting agents are usually administered by inhalation, for example, with a metered-dose inhaler or a powder inhaler. They should be used only when needed. An increase in administration … Antiasthmatics
Products Cromoglicic acid eye drops have been approved in many countries since 1977 (Opticrom, generic). Structure and properties The eye drops contain sodium cromoglicate (C23H14Na2O11, Mr = 512.3 g/mol), a white, crystalline, hygroscopic powder that is soluble in water. It is the disodium salt of cromoglicic acid. Effects Sodium cromoglicate (ATC S01GX01) is mast cell … Cromoglicic Acid Eye Drops
Products Multivitamin preparations are commercially available in the form of tablets, effervescent tablets, chewable tablets and juice, among others. Among the best-known brands in many countries are, for example, Burgerstein CELA, Centrum and Supradyn. Some products are approved as medicines and others as dietary supplements. Supradyn (Bayer) was originally manufactured by Roche and has been … Multivitamin Supplements
Products Ambroxol is commercially available in the form of lozenges, sustained-release capsules, and syrup (e.g., Mucosolvon), among others. It has been approved in many countries since 1982. Structure and properties Ambroxol (C13H18Br2N2O, Mr = 378.1 g/mol) is present in drugs as ambroxol hydrochloride, a white to yellowish crystalline powder that is sparingly soluble in water. … Ambroxol (Mucosolvan)
Effects Iron chelators form complexes with iron ions and deliver them to excretion as a complex. Indications Chronic iron overload T.T. chronic aluminum overload Acute iron poisoning Hemosiderosis (iron deposition in the form of hemosiderin). Agents Deferoxamine (Desferal) Deferiprone (Ferriprox) Deferasirox (Exjade)
Products Oligomannate was approved in China in 2019 in the form of capsules (Shanghai Green Valley Pharmaceuticals). The group led by Prof. Geng Meiyu at the Shanghai Institute of Materia Medica spent more than 20 years on the research. This is the first new oral Alzheimer’s drug since 2003, and another Phase III clinical trial … Oligomannate
Products Polidocanol is commercially available as a solution for injection (Sclerovein, Aethoxysclerol). It has been approved in many countries since 1967. Synonyms for the active ingredient include polidocanol 600 and lauromacrogol 400. Structure and properties Polidocanol is a mixture of ethers of various macrogols with fatty alcohols, mainly lauryl alcohol (C12H26O). It exists as a … Polidocanol (Vein Sclerotherapy)
Products Trametinib was approved in the form of film-coated tablets in the United States in 2013, in the EU in 2014, and in many countries in 2016 (Mekinist). Structure and properties Trametinib (C26H23FIN5O4, Mr = 615.4 g/mol) is a pyridine and a pyrimidine derivative. It is present in the drug product as trametinib dimethyl sulfoxide, … Trametinib
