Products In many countries, no drugs containing warfarin are approved, and the closely related phenprocoumon (Marcoumar) is mainly used. However, warfarin is commonly used in other countries, particularly the United States, and is commercially available in tablet form (Coumadin) and other forms. It was approved in the United States in 1954. Structure and properties Warfarin … Warfarin
Definition Plasma concentration is the concentration of a pharmaceutical agent in blood plasma at a given time after administration. Plasma is the liquid portion of blood excluding its cellular components. Concentration is typically expressed in µg/ml. Plasma concentration-time curves If plasma levels are measured several times after administration, a plasma concentration-time curve can be constructed … Plasma Concentration
Products Pyrantel is commercially available in the form of chewable tablets and oral suspension and is available in many countries without a doctor’s prescription (Cobantril, originally: Combantrin). It has been approved since 1971 and is also commonly used as a veterinary drug. Structure and properties Pyrantel (C11H14N2S, Mr = 206.3 g/mol) is present in the … Pyrantel
Products Ibalizumab was approved in the United States in 2018 and in the EU in 2019 (Trogarzo, TaiMed Biologics). Structure and properties Ibalizumab is a humanized IgG4 monoclonal antibody. It is produced by biotechnological methods. Unlike most antiviral agents, it is directed against an endogenous drug target rather than the virus. Effects Ibalizumab has antiviral … Ibalizumab
Products Phenprocoumon is commercially available in tablet form (Marcoumar). It has been approved in many countries since 1953. Warfarin (Coumadin) is more common in some countries. Structure and properties Phenprocoumon (C18H16O3, Mr = 280.32 g/mol) is a derivative of 4-hydroxycoumarin and a racemate. The -enantiomer is pharmacologically more active. Phenprocoumon exists as a fine, white, … Phenprocoumon
Products The selective serotonin reuptake inhibitors (SSRIs) are mainly taken in the form of film-coated tablets or capsules. In addition, other dosage forms such as dispersible tablets, melting tablets and drops are available. Zimelidin was the first to be developed in the 1970s and was approved in the early 1980s. Sales had to be discontinued … Selective Serotonin Reuptake Inhibitor
