Probenecid: Effects, Uses & Risks

Probenecid is a second-line drug for hyperuricemia and gout. It inhibits the URAT1 exchanger in the kidney, increasing the release of urea into the urine while decreasing the excretion of organic anions. Probenecid interacts with numerous other drugs. What is probenecid? Because the drug stimulates the body to excrete uric acid, probenecid belongs to the … Probenecid: Effects, Uses & Risks

Ossification

General information Ossification is the formation of boils. A distinction is made between the formation of bone from connective tissue, which is called desmal ossification, and chondral ossification, in which bone is formed from existing cartilage. Usually, ossification is a natural process that builds up the incomplete skeleton, especially in childhood. However, increased ossification can … Ossification

Desmal Ossification | Ossification

Desmal Ossification The desmal ossification is made of connective tissue. This is formed by mesenchymal cells. During ossification, the cells are first positioned close to each other and are then increasingly better supplied with blood. Then the mesenchymal cells change into osteoblasts, the cells that form bone. These then first form the organic parts of … Desmal Ossification | Ossification

Disturbances of the ossification | Ossification

Disturbances of the ossification Among the diseases that affect ossification, a distinction is made between diseases that alter normal ossification and diseases that lead to excessive ossification. A typical disorder of ossification is achondroplasia, which leads to premature closure of the epiphyseal joints. The absence of cartilage in the long bones prevents the bone from … Disturbances of the ossification | Ossification

Function of the kidney

Definition The paired kidneys are part of the urinary system and are located at the level of the 11th and 12th rib below the diaphragm. A fat capsule envelops both kidneys and adrenal glands. Pain resulting from kidney disease usually projects onto the lumbar region of the middle back. The function of the kidneys is … Function of the kidney

Function of the renal corpuscles | Function of the kidney

Function of the renal corpuscles The functional units of the renal cortex are about one million nephrons, which in turn are composed of the renal corpuscles (Corpusculum renale) and renal tubules (Tubulus renale). The formation of the primary urine takes place in the renal corpuscles. Here the blood flows through a vascular cluster, the glomerulum, … Function of the renal corpuscles | Function of the kidney

The influence of alcohol on the kidneys | Function of the kidney

The influence of alcohol on the kidneys Most of the alcohol absorbed is broken down in the liver to acetaldehyde. A smaller part, about one tenth, is excreted via the kidneys and lungs. If alcohol is consumed in moderation, there is no danger to the kidneys. Excessive alcohol consumption, on the other hand, causes lasting … The influence of alcohol on the kidneys | Function of the kidney

Alosetron: Effects, Uses & Risks

The drug alosetron acts on tissue hormones from the serotonin group, which are predominantly found in the human digestive tract and here control the transport of stool through the intestine. The active ingredient is only administered in the USA under strict conditions to patients with severe irritable bowel syndrome. The reason: serious side effects are … Alosetron: Effects, Uses & Risks