Calmodulin: Function & Diseases

The complex cellular and physiological processes in living organisms require finely tuned regulation at the molecular level to ensure the adaptability of, for example, an animal or a plant to its habitat. To this end, numerous molecules exist that intervene in processes such as cell communication, metabolism or cell division. One of these molecules is … Calmodulin: Function & Diseases

Simvastatin: Effects, Uses & Risks

Simvastatin is a classic statin and is used as a cholesterol-lowering agent. It was approved in 1990 and is used relatively frequently. What is simvastatin? Simvastatin, chemically (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl-2,2-dimethylbutanoate, is a drug used primarily as a cholesterol-lowering agent. Simvastatin is structurally derived from the naturally occurring monacolin K, also known as lovastatin. Simvastatin is partially synthetically … Simvastatin: Effects, Uses & Risks

Valganciclovir: Effects, Uses & Risks

Valganciclovir is a virostatic agent used to treat cytomegalovirus retinitis (inclusion body disease) occurring in AIDS patients. The drug belongs to the group of nucleoside analogues and is widely used. As a prodrug of the substance ganciclovir, it has essentially the same effects and side effects as the latter. What is valganciclovir? Valganciclovir is a … Valganciclovir: Effects, Uses & Risks

Osteocytes: Structure, Function & Diseases

Osteocytes are mature bone cells enclosed by osteoblasts of the bone matrix. When bone is defective, osteocytes die because of inadequate nutrient supply, prompting the bone-degrading osteoclasts. Pathologic osteocytes may be relevant to diseases such as osteoporosis. What are osteocytes? Human bone is alive. Immature osteoblasts form what is called the bone matrix. This network … Osteocytes: Structure, Function & Diseases

Potato: Intolerance & Allergy

Potatoes have become indispensable as a tasty and nutritious staple food and ingredient in numerous dishes. The inexpensive tubers can be easily grown and also serve as animal feed and raw material for industrial use. On average, every German eats around 60 kilograms of potatoes every year. What you should know about potatoes The low-calorie … Potato: Intolerance & Allergy

Orange: Intolerance & Allergy

Orange is a fruit that is also known as orange. It belongs to the genus of citrus plants and originates from China. This is what you should know about the orange The orange is a fruit that is also known by the name orange. It belongs to the genus of citrus plants and originated in … Orange: Intolerance & Allergy

Moxifloxacin: Effects, Uses & Risks

Moxifloxacin is an antibiotic agent that belongs to the subgroup of fluoroquinolones. Specifically, the drug belongs to the fourth-generation fluoroquinolones. Fluoroquinolones are antibiotic gyrase inhibitors and are suitable for the treatment of various diseases and conditions. The drug is to be used only after prescription by a doctor. What is moxifloxacin? The drug moxifloxacin belongs … Moxifloxacin: Effects, Uses & Risks

Pegaspargases

Products Pegaspargase is commercially available as an injectable (Oncaspar). The drug was approved in the United States in 2006, in the EU in 2016, and in many countries in 2017. Structure and properties Pegaspargase (PEG-L-asparaginase) is the pegylated enzyme L-asparaginase. The PEG units are covalently attached to the enzyme. Effects Pegaspargase (ATC L01XX24) has antileukemic … Pegaspargases

Tipranavir: Effects, Uses & Risks

The active medical ingredient Tipranavir is a drug that is used to treat people with HIV type 1. It is used as part of a combination antiretroviral therapy. The drug Tipranavir is available on the pharmacological market under the trade name Aptivus and is distributed by the producer Boehringer. The active ingredient tipranavir is considered … Tipranavir: Effects, Uses & Risks