Carbapeneme

Effects Carbapenems (ATC J01DH) are bactericidal against aerobic and anaerobic Gram-positive and Gram-negative pathogens. Effects are based on binding to penicillin-binding proteins (PBP) and inhibition of bacterial cell wall synthesis, resulting in bacterial dissolution and death. Imipenem, the first representative of the drug group, is degraded by the renal enzyme dehydropeptidase-I (DHP-I). It is therefore … Carbapeneme

Tebipenem: Effects, Uses & Risks

Tebipenem is a medicinal agent that belongs to the group of carbapenems. Tebipenem is thus a so-called beta-lactam antibiotic, which goes back to penicillin. It is used to fight infectious diseases caused by bacteria. What is tebipenem? Tebipenem is an antibiotic that is administered to treat infectious diseases. The chemical molecular formula of the substance … Tebipenem: Effects, Uses & Risks

Ertapenem

Products Ertapenem is commercially available as a lyophylisate for the preparation of an infusion solution (Invanz). It has been approved in many countries since 2003. Structure and properties Ertapenem (C22H25N3O7S, Mr = 475.5 g/mol) is present in drugs as ertapenem sodium, a white, hygroscopic, weakly crystalline powder that is soluble in water. It is a … Ertapenem

Doripenem: Effects, Uses & Risks

Doripenem is an active substance, which belongs to the group of carbapenems. Consequently, Doripenem is an antibiotic that is used, among other things, for the treatment of infectious diseases (e.g., pneumonia, urinary tract infections, or abdominal infections). It is administered in the European Union primarily by infusion. What is doripenem? Doripenem is an antibiotic belonging … Doripenem: Effects, Uses & Risks

Ertapenem: Effects, Uses & Risks

Ertapenem is a medicinal agent of the carbapenems group. Preparations containing the drug are used, among other things, for the treatment of intra-abdominal infections, acute gynecological infections, community-acquired pneumonia, and diabetic foot therapy. In addition, ertapenem is used preventively to prevent abdominal infection before surgery. What is ertapenem? Ertapenem is classified as belonging to the … Ertapenem: Effects, Uses & Risks