Definition Triggered by a chronic vitamin B12 deficiency, funicular myelosis results in the regression of certain spinal cord areas. Symptoms Funicular myelosis is characterized by a breakdown of the myelin sheaths surrounding the nerves (so-called demyelination). If this sheathing of the nerve cells is missing, malfunctions and short circuits occur in the transmission of nerve … Funicular myelosis
Diagnostics During the physical examination, the following features of funicular myelosis are particularly noticeable: If the water in the spinal canal (liquor) is also examined, two thirds of the affected patients show an increase in protein. The measurement of nerve conduction velocity (electroneurography) shows a slowdown in about three-quarters of the patients, which is partly … Diagnostics | Funicular myelosis
Therapy Funicular myelosis is treated with vitamin B12 injections or infusions. This substitution may be necessary for years until the actual cause of the reduced vitamin B12 content in the body can be eliminated. Prognosis The prognosis for funicular myelosis is very good and a complete cure is possible if the clinical picture or the … Therapy | Funicular myelosis
In medicine, remyelination describes a process in which the body partially restores the insulating myelin layer that normally surrounds nerve fibers (axons). Often, remyelination is not completely successful, so permanent damage is possible. Various diseases (for example, multiple sclerosis, funicular myelosis, or Miller-Fisher syndrome) can affect the myelin sheaths of nerve cells. What is remyelination? … Remyelination: Function, Role & Diseases
Schwann cells are a type of glial cell, such as those that serve to stabilize and nourish nerve fibers in the peripheral nervous system. They also wrap around the axons of medullary nerve fibers, providing them with insulating myelin. In inflammatory demyelinating diseases in the peripheral nervous system, the myelin of the cells is destroyed … Schwann Cell: Structure, Function & Diseases
Aquacobalamin is one of the B12 vitamins. As such, it participates in the synthesis of amino acids. Deficiency of aquacobalamin and other cobalamins can lead to severe disorders that may include irreversible neurological damage. What is aquacobalamin? Aquacobalamin or aquocobalamin belongs to the vitamin B12 group, which are also known as cobalamins in biology. The … Aquacobalamin: Function & Diseases
Funicular myelosis is a degenerative breakdown of spinal cord structures due to chronic vitamin B12 deficiency. The condition manifests mainly after the fifth decade of life. What is funicular myelosis? Funicular myelosis is the degeneration of specific areas of the spinal cord (posterior cord, pyramidal side cords), which is generally due to long-term vitamin B12 … Funicular Myelosis: Causes, Symptoms & Treatment
