Antiasthmatics

1. symptom treatment Beta2-sympathomimetics are derived from epinephrine. They selectively stimulate the adrenergic β2-receptors of bronchial muscles and thus have a bronchospasmolytic effect. For rapid symptom relief, fast-acting agents are usually administered by inhalation, for example, with a metered-dose inhaler or a powder inhaler. They should be used only when needed. An increase in administration … Antiasthmatics

Chronic Obstructive Pulmonary Disease

Symptoms Possible symptoms of chronic obstructive pulmonary disease (COPD) include a chronic cough, mucus production, sputum, shortness of breath, chest tightness, breath sounds, lack of energy, and sleep disturbances. The symptoms often worsen with physical exertion. An acute worsening of chronic symptoms is referred to as an exacerbation. In addition, numerous systemic and extrapulmonary concomitant … Chronic Obstructive Pulmonary Disease

Formoterol

Products Formoterol is commercially available in the form of capsules for inhalation (Foradil) and as a powder inhaler (Oxis). Furthermore, combination products with budesonide (Symbicort Turbuhaler, Vannair Dosieraerosol) and fluticasone propionate are available (Formoterol Dosieraerosol). Formoterol is also combined with beclometasone fixed, see under beclometasone and formoterol (Foster). Furthermore, in 2020, a fixed combination with … Formoterol

Glycopyrronium Bromide

Products Glycopyrronium bromide is commercially available in the form of hard capsules with a powder for inhalation (Seebri Breezhaler). It was approved in the EU in 2012 and in many countries in April 2013. Glycopyrronium bromide is also combined fixed with indacaterol (Ultibro Breezhaler, approved in many countries in 2014). In 2020, a combination of … Glycopyrronium Bromide

Anticholinergics: Effect, Uses & Risks

Anticholinergics are widely used in medicine because of their effect in the parasympathetic nervous system. However, the side effects should not be underestimated. What are anticholinergics? Anticholinergics, for example, cause a decrease in bowel activity. Anticholinergics are substances that inhibit the main neurotransmitter acetylcholine in the parasympathetic nervous system. As a part of the autonomic … Anticholinergics: Effect, Uses & Risks

LABA

Products LABA is an acronym for , which means long-acting beta agonists (sympathomimetics). LABAs are mainly marketed as inhaled preparations (powders, solutions) administered with an inhaler such as a metered-dose inhaler, diskus, respimat, breezhaler, or ellipta. Some may also be given perorally. Salmeterol and formoterol were the first agents from this group to be approved … LABA

LAMA

Products LAMAs are commercially available as powders and inhalation solutions and are administered with a specially designed inhaler or with a nebulizer (nebulizer). LAMA is the acronym for , which means long-acting antagonists at muscarinic receptors. Structure and properties LAMAs are derived from the parasympatholytic atropine, which is a natural plant constituent found in various … LAMA

Beclometasone

Products Beclometasone is commercially available as a drug for inhalation and as a nasal spray (Qvar, Beclo Orion). It has been approved in many countries since 1998. This article refers to inhalation. See also under beclometasone nasal spray. Beclometasone is also combined with formoterol fix; see under Beclometasone and Formoterol (Foster). In 2020, a fixed … Beclometasone

Mometasone

Products Mometasone furoate is commercially available as a cream, ointment, emulsion, and solution (Elocom, Monovo, Ovixan). It has been approved in many countries since 1989. This article refers to use on the skin. Nasal sprays are also available; see mometasone nasal spray. In 2020, a fixed combination with indacaterol was approved for asthma therapy (Atectura … Mometasone

Ipratropium Bromide

Products Ipratropium bromide is commercially available as an inhalation solution, metered-dose inhaler, and nasal spray (Atrovent, Rhinovent, generics). Combination preparations with beta2-sympathomimetics are also commercially available (Dospir, Berodual N, generics). Pharmacies also produce inhalation solutions with ipratropium bromide as extemporaneous preparations. The active ingredient has been approved in many countries since 1978. Structure and properties … Ipratropium Bromide

Glycopyrronium Bromide: Effects, Uses & Risks

Glycopyrronium bromide is a drug of the parasympatholytic group. It is used as an agent to reduce secretions in chronic obstructive pulmonary disease (COPD). As an anticholinergic, it suppresses the action of acetylcholine in the parasympathetic nervous system. What is glycopyrronium bromide? Glycopyrronium bromide is used as an active ingredient to reduce secretions in chronic … Glycopyrronium Bromide: Effects, Uses & Risks

Parasympatholytics

Products Parasympatholytics are commercially available, for example, in the form of tablets, capsules, solutions, as inhalation preparations, injection solutions, and eye drops. This article refers to antagonists at muscarinic acetylcholine receptors. Antagonists at nicotinic acetylcholine receptors, such as ganglion blockers, are discussed separately. Structure and properties Many parasympatholytics are structurally derived from atropine, a natural … Parasympatholytics