Products Peginterferon alfa-2a is commercially available as an injectable (Pegasys). It has been approved in many countries since 2002. Structure and properties Peginterferon alfa-2a is a covalent conjugate of the recombinant protein interferon alfa-2a and a branched monomethoxy polyethylene glycol (PEG). It has a molecular mass of approximately 60 kDa and is derived from by … Peginterferon Alfa-2A
Products Peginterferon alfa-2b was commercially available as an injectable (PegIntron). It had been approved in many countries since 2002. Structure and properties Peginterferon alfa-2b is a covalent conjugate composed of the recombinant protein interferon alfa-2b and a monomethoxy polyethylene glycol (PEG). It has a molecular weight of approximately 31 kDa. Peginterferon alfa-2b is obtained from … Peginterferon Alfa-2B
Products Asunaprevir is not currently registered in many countries. It has been approved in Japan since 2014 (Sunvepra, Bristol-Myers Squibb) and is used in combination with daclatasvir (Daklinza) as an interferon and ribavirin-free treatment. Structure and properties Asunaprevir (C35H46ClN5O9S, Mr = 748.3 g/mol) Effects Asunaprevir has antiviral properties. The effects are due to selective and … Asunaprevir
Symptoms The possible symptoms of acute hepatitis include: Fatigue Pain, fever Nausea, vomiting, lack of appetite Light stools, dark urine Jaundice Swelling of the liver and spleen The disease usually lasts less than two months, but can last for several months. Unlike other infectious liver inflammations such as hepatitis B and hepatitis C, it does … Hepatitis A Symptoms, Causes and Treatment
Symptoms Most patients have no symptoms. The disease may manifest as fatigue, nausea, loss of appetite, muscle and joint pain, and weight loss. Potential longer-term dangerous complications of chronic infection that can develop over years include cirrhosis and liver cancer. This eventually often makes liver transplantation necessary. Causes The cause of the symptoms is infection … Hepatitis C Symptoms, Causes and Treatment
Products Telaprevir is commercially available in the form of film-coated tablets (Incivo). It was approved in many countries in 2011. Structure and properties Telaprevir (C36H53N7O6, Mr = 679.8 g/mol) is a peptidomimetic and a ketoamide. It exists as a white crystalline powder that is sparingly soluble in water. Telaprevir is converted in the body to … Telaprevir
Products Glecaprevir was approved in the United States, many countries, and the EU in 2017 as a fixed-dose combination with pibrentasvir in film-coated tablet form (Maviret). Structure and properties Glecaprevir (C38H46F4N6O9S, Mr = 838.9 g/mol) exists as a white crystalline powder. Effects Glecaprevir has antiviral properties. The effects are due to inhibition of the viral … Glecaprevir
Pedicure is a medical foot care to maintain the health of the skin of the foot with special attention to toenails and calluses. In many cases, it is performed foot care at home under their own direction. Professional foot care by trained professionals is called podiatry. What is pedicure? Pedicure is a medical foot care … Pedicure: Treatment, Effect & Risks
Products Interferon alfa-2a is commercially available as an injectable (Roferon-A). It has been approved in many countries since 1997. Structure and properties Interferon alfa-2a is a recombinant protein obtained from a -strain by biotechnological methods. It consists of 165 amino acids and has a molecular mass of approximately 19 kDa. Effects Interferon alfa-2a (ATC L03AB04) … Interferon Alfa-2A
Products Interferon alfa-2b was commercially available as a drug for injection or infusion (Intron-A). It was approved in many countries as of 1998. In other countries, the drug remains available. Structure and properties Interferon alfa-2b is a recombinant, water-soluble protein obtained from a -strain by biotechnological methods. It consists of 165 amino acids and has … Interferon Alfa-2B
Products Interferons are sold exclusively as injectables, for example, in the form of prefilled syringes. They are stored in the refrigerator at 2 to 8°C. The body’s own cytokines were discovered in the 1950s. Structure and properties Interferons are proteins with a molecular weight between 15 to 21 kDa. They are now produced by biotechnological … Interferons
Products Pibrentasvir was approved in the United States, many countries, and the EU in 2017 as a fixed-dose combination with glecaprevir in film-coated tablet form (Maviret). Structure and properties Pibrentasvir (C57H65F5N10O8, Mr = 1113.2 g/mol) exists as a white to slightly yellow crystalline powder. Effects Pibrentasvir has antiviral properties. The effects are due to binding … Pibrentasvir
