Products Indinavir is commercially available in capsule form (Crixivan). It has been approved in many countries since 1996. Structure and properties Indinavir (C36H47N5O4, Mr = 613.8 g/mol) is present in drugs as indinavir sulfate, a white crystalline powder that is very soluble in water. Effects Indinavir (ATC J05AE02) has antiviral properties. The effects are due … Indinavir
Products Most HIV protease inhibitors are commercially available in tablet or capsule form. In addition, a few liquid dosage forms are available for ingestion. Saquinavir (Invirase) was the first to be lanicized in 1995. Structure and properties The first HIV protease inhibitors were modeled on the natural peptide substrate of the HIV protease. The protease … HIV Protease Inhibitor
Background The human organism has several mechanisms to metabolize endogenous and foreign substances. One of these mechanisms is glucuronidation, which occurs primarily in the liver. In this process, enzymes from the superfamily of UDP-glucuronosyltransferases (UGT) transfer a molecule of glucuronic acid from UDP-glucuronic acid to the substrate. Using acetaminophen as an example, alcohols, phenols, carboxylic … Meulengracht’s Disease
Amprenavir is a medical agent and belongs to the group of HIV protease inhibitors. The drug is used to treat HIV infection. What is amprenavir? Amprenavir is a medical agent and belongs to the group of HIV protease inhibitors. The drug is used to treat HIV infection. Amprenavir is a drug marketed in Germany, Austria, … Amprenavir: Effects, Uses & Risks
P-glycoprotein P-glycoprotein (P-gp, MDR1) is a primary active efflux transporter with a molecular weight of 170 kDa, belonging to the ABC superfamily and consisting of 1280 amino acids. P-gp is the product of the -gene (formerly: ). P is for , ABC is for . Occurrence P-glycoprotein is found on various tissues of the human … P-Glycoprotein
Indinavir belongs to the protease inhibitors. The active medical ingredient is used to treat HIV infection. What is indinavir? Indinavir belongs to the protease inhibitors. The medical agent is used for the therapy of HIV infections. Indinavir is the name given to an antiviral drug that belongs to the group of HIV protease inhibitors and … Indinavir: Effects, Uses & Risks
