Products Ibandronate is commercially available as film-coated tablets (monthly tablets containing 150 mg of ibandronic acid) and as a solution for injection (Bonviva, generics). The daily tablets containing 2.5 mg of active ingredient are no longer available. This article refers to oral and monthly osteoporosis therapy. Ibandronate is also used in tumor treatment. Ibandronate was … Ibandronate
Products Norepinephrine is commercially available as a solution for injection in many countries. It is also known as norepinephrine. Structure and properties Norepinephrine (C8H11NO3, Mr = 169.2 g/mol) is a demethylated epinephrine. It is present in drugs as noradrenaline tartrate, a white crystalline powder that is readily soluble in water. Effects Norepinephrine (ATC C01CA03) has … Norepinephrine
Products Diazepam is commercially available in tablet, drop, solution for injection, and enema form (Valium, generic). It has been approved in many countries since 1962. In 2020, a diazepam nasal spray was released in the United States. Diazepam was developed by Leo Sternbach at Hoffmann-La Roche as the second member of the benzodiazepine group. Structure … Diazepam: Drug Effects, Side Effects, Dosage and Uses
Products Denosumab is commercially available as a solution for injection in a prefilled syringe (Prolia). The antibody was approved in many countries, in the United States, and in the EU in 2010. Denosumab is also used in tumor therapy (Xgeva). This article relates to osteoporosis treatment. Structure and properties Denosumab is a human IgG2 monoclonal … Denosumab
Products Fremanezumab was approved in the United States in 2018 and in the EU and Switzerland in 2019 as a solution for injection for subcutaneous use (Ajovy). Structure and properties Fremanezumab is a humanized IgG2Δa/kappa monoclonal antibody directed against CGRP (calcitonin gene-related peptide). The antibody is produced by biotechnological methods, consists of 1324 amino acids, … Fremanezumab
Products Salbutamol is commercially available as a metered-dose inhaler, inhalation solution, diskus, syrup, infusion concentrate, and solution for injection (Ventolin, generics). It has been approved in many countries since 1972 and is also known as albuterol in English-speaking countries. Salbutamol is the precursor of salmeterol and vilanterol (all GlaxoSmithKline). Structure and properties Salbutamol (C13H21NO3, Mr … Salbutamol: Drug Effects, Side Effects, Dosage and Uses
Products Salmcalcitonin is commercially available as a nasal spray and solution for injection (Miacalcic). It has been approved in many countries since 1976. Structure and properties The drug does not contain the human thyroid hormone calcitonin, but salmon calcitonin, also known as salmcalcitonin. It is a synthetic polypeptide consisting of 32 amino acids (C145H240N44O48S2, Mr … Salmcalcitonin
Products Sarilumab was approved in the United States and EU in 2017 and in many countries in 2018 as a solution for injection (Kevzara, prefilled syringe, prefilled pen). Structure and properties Sarilumab is a human IgG1 monoclonal antibody with a molecular mass of 150 kDa. It is produced by biotechnological methods. Effects Sarilumab (ATC L04AC14) … Sarilumab
Products Flecainide is commercially available as tablets and as a solution for injection (Tambocor). It has been approved in many countries since 1984. Structure and properties Flecainide (C17H20F6N2O3, Mr = 414.3 g/mol) is present in drugs as flecainide acetate, a white, crystalline, and very hygroscopic powder that is soluble in water. It is an amide-type … Flecainide
Products Nandrolone is commercially available as a solution for injection (Deca-Durabolin). It has been approved in many countries since 1960. Structure and properties Nandrolone (C18H26O2, Mr = 274.4 g/mol) is present in the drug in the form of the long-acting prodrug nandrolone decanoate, a white crystalline powder that is practically insoluble in water because of … Nandrolone
