Products Dupilumab was approved as a solution for injection in the United States and EU in 2017 and in many countries in 2019 (Dupixent). Structure and properties Dupilumab is a human recombinant IgG4 monoclonal antibody with a molecular mass of 147 kDa. It is produced by biotechnological methods. Effects Dupilumab (ATC D11AH05) has anti-inflammatory and … Dupilumab
Products Ganirelix was commercially available as a solution for injection in prefilled syringes (Orgalutran). It was approved in many countries since 2000. It was discontinued in 2019. Structure and properties Ganirelix is a decapeptide and a derivative of gonadotropin-releasing hormone (GnRH) produced by the hypothalamus. It differs from the natural hormone at positions 1, 2, … Ganirelix
Products Midazolam is commercially available as film-coated tablets and as a solution for injection (Dormicum, generic). It has been approved in many countries since 1982. Midazolam nasal spray has not yet been registered in many countries and must be prepared in a pharmacy as an extemporaneous formulation or imported. In 2012, a solution for use … Midazolam
Products Metoprolol is commercially available as sustained-release tablets and as a solution for injection (Beloc ZOK, Lopresor, generics). It has been approved in many countries since 1975. Structure and properties Metoprolol (C15H25NO3, Mr = 267.36 g/mol) is a racemate. It is present in drugs in the form of the salts metoprolol succinate or metoprolol tartrate. … Metoprolol: Drug Effects, Side Effects, Dosage and Uses
Products Doxycycline is commercially available in the form of tablets, capsules, and as a solution for injection (vibramycin, vibravenous, generic). It has been approved in many countries since 1972. Structure and properties Doxycycline (C22H24N2O8, Mr = 444.4 g/mol) is usually present in drugs as doxycycline hyclate. Some drugs also contain doxycycline monohydrate. These are yellow … Doxycycline: Drug Effects, Side Effects, Dosage and Uses
Products Numerous drugs are available in the form of prefilled syringes. These include, for example, low-molecular-weight heparins, epoetins, methotrexate, TNF-alpha inhibitors, and vaccines. Many, but not all, must be stored in the refrigerator. These should not be frozen. Prefilled syringes should be stored in the package to protect them from light. Structure and properties Prefilled … Prefilled Syringes
Products Dexketoprofen is commercially available as film-coated tablets and as a solution for injection (Ketesse). It has been approved in many countries since 2000. In 2017, a fixed combination with tramadol was registered; see Tramadol Dexketoprofen (Skudexa). Structure and properties Dexketoprofen (C16H14O3, Mr = 254.3) is the active -enantiomer of ketoprofen, which exists as a … Dexketoprofen
Products C1 esterase inhibitor is commercially available as a powder and solvent for the preparation of a solution for injection (Berinert, Cinryze). It has been approved in many countries since 1993. Structure and properties C1 esterase inhibitor is a glycoprotein with a molecular mass of 105 kDa, consisting of 478 amino acids and occurring naturally … C1 Esterase Inhibitor
Products Atosiban is commercially available as a solution for injection and as an infusion concentrate (Tractocile). It has been approved in many countries since 2002. Generic versions were registered in 2018. Structure and properties Atosiban (C43H67N11O12S2, Mr = 994.2 g/mol) is a synthetic nonapeptide derived from oxytocin. Effects Atosiban (ATC G02CX01) has labor inhibitory properties. … Atosiban
Products Turoctocog alfa is commercially available as a powder and solvent for solution for injection (NovoEight). It has been approved in many countries since 2014. See also under turoctocog alfa pegol (pegylated drug). Structure and properties Turoctocog alfa is an activated human blood coagulation factor VIII produced by biotechnological methods and truncated at the B … Turoctocog Alfa
Products Turoctocog alfa pegol was approved in the US, EU, and many countries in 2019 as a powder and solvent for solution for injection (Esperoct). Structure and properties Turoctocog alfa pegol is a recombinant and modified human factor VIII (rFVIII) produced by biotechnological methods. A polyethylene glycol (PEG) with a molecular mass of 40 kDa … Turoctocog Alfa Pegol
Products Galcanezumab was approved in the United States and EU in 2018 and in many countries in 2019 as a solution for injection in a prefilled pen and a prefilled syringe (Emgality, Eli Lilly). Structure and properties Galcanezumab is a humanized IgG4 monoclonal antibody with a molecular mass of 147 kDa against CGRP. It is … Galcanezumab
