laropiprant

Nicotinic Acid

Products Nicotinic acid was commercially available in the form of modified-release tablets as a fixed combination with laropiprant (Tredaptive, 1000 mg/20 mg). The combination was approved in many countries in 2009, replacing earlier monopreparations such as Niaspan. The drug was withdrawn from the market on January 31, 2013. Structure and properties Nicotinic acid (C5H5NO2, Mr … Nicotinic Acid

Laropiprant

Products Laropiprant was included in Tredaptive in combination with nicotinic acid. The drug was approved in many countries in 2009 and was withdrawn from the market in late January 2013 see under Nicotinic Acid. Structure and properties Laropiprant (C21H19ClFNO4S, Mr = 435.9 g/mol) Effects During therapy with the lipid-lowering drug nicotinic acid (niacin), a flush, … Laropiprant