Products Zileuton is commercially available in the United States in tablet and powder form (Zyflo). It is not currently approved in many countries. Structure and properties Zileuton (C11H12N2O2S, Mr = 236.3 g/mol) is an almost odorless, white, crystalline powder that is practically insoluble in water. It exists as a racemate. Both enantiomers are pharmacologically active. … Zileuton
Symptoms A cat allergy manifests itself similarly to hay fever. Possible symptoms include an allergic rhinitis, sneezing, coughing, asthma, shortness of breath, wheezing, allergic conjunctivitis, eye watering, hives, dermatitis, rash when scratching, and itching. Complications include the development of asthma and chronic sinusitis. Patients often suffer from other allergies. Causes The cause is type 1 … Cat Allergy
Symptoms A dust mite allergy manifests itself in allergic symptoms. These include: Perennial allergic rhinitis: sneezing, runny nose, in the later course of the disease rather a chronically stuffy nose. Allergic conjunctivitis: itchy, watery, swollen and red eyes. Sinusitis with headache and facial pain Lower respiratory tract: cough, bronchial asthma. Itching, rash, eczema, exacerbation of … House Dust Mite Allergy
Products Anti-allergy medications are available in numerous dosage forms. These include tablets, capsules, solutions, suspensions, nasal sprays, eye drops, inhalation preparations, and injectables. Structure and properties Antiallergic drugs do not have a uniform chemical structure. However, several groups within the class can be identified (see below). Effects Antiallergic drugs have antiallergic, antiinflammatory, immunosuppressive, antihistamine, and … Antiallergics
1. symptom treatment Beta2-sympathomimetics are derived from epinephrine. They selectively stimulate the adrenergic β2-receptors of bronchial muscles and thus have a bronchospasmolytic effect. For rapid symptom relief, fast-acting agents are usually administered by inhalation, for example, with a metered-dose inhaler or a powder inhaler. They should be used only when needed. An increase in administration … Antiasthmatics
Symptoms Nasal polyps are usually bilateral and localized benign mucosal protrusions of the nasal cavity or sinuses. The leading symptom is nasal constriction leading to a change in voice quality. Other possible symptoms include a watery discharge (rhinorrhea), impaired sense of smell and taste, pain and a feeling of fullness in the head. Nasal polyps … Nasal Polyps
Products Zafirlukast was commercially available in the form of film-coated tablets (Accolate, off label). It was approved in many countries in 1998. It was discontinued from distribution in 2019. Montelukast is a suitable substitute. Structure and properties Zafirlukast (C31H33N3O6S, Mr = 575.7 g/mol) exists as a fine, white to pale yellow, amorphous powder that is … Zafirlukast
Symptoms Allergies can affect various organ systems: Skin: hives with wheals, itching, redness, swelling (edema), eczema. Nose: runny and stuffy nose, sneezing, itching. Airways: bronchoconstriction, shortness of breath, cough, asthma. Digestive tract: diarrhea, vomiting, indigestion. Eyes: Allergic conjunctivitis, redness, tearing. Cardiovascular: Drop in blood pressure, rapid heartbeat Mouth, mucous membrane: Burning, furry feeling, swelling. Throat: … Allergy
Symptoms Possible symptoms of hay fever include: Allergic rhinitis: itchy, runny or stuffy nose, sneezing. Allergic conjunctivitis: red, itchy, watery eyes. Cough, mucus formation Itching in the mouth Swollen, blue discolored skin under the eyes Fatigue Sleep disturbance due to the discomfort Hay fever is often accompanied by other inflammatory diseases of the mucous membranes. … Hay Fever Causes
Symptoms Urticaria is a skin disorder that manifests itself in the following symptoms: Temporary wheals with a diameter of millimeters to centimeters, which recede on their own within minutes to hours. Itching, burning and redness of the skin. Angioedema, which is a swelling of the lower skin or mucosal tissue that may be accompanied by … Urticaria: Causes and Treatment
Products Leukotriene antagonists are commercially available as film-coated tablets, granules, and chewable tablets. Structure and properties The active ingredients do not have a uniform chemical structure. Effects The leukotriene antagonists (ATC R03DC) have antiasthmatic, anti-inflammatory, bronchodilator, and antiallergic properties. They bind to the CysLT1 receptor, thereby inhibiting the effects of the cysteinyl leukotrienes LTC4, LTD4, … Leukotriene Antagonists
Effects Leukotriene synthesis inhibitors are antiallergic and anti-inflammatory. Mechanism of action Inhibition of the synthesis of leukotrienes from arachidonic acid by inhibition of 5-lipoxygenase. Indications For prevention and long-term therapy of asthma in adults and children over 12 years of age. Active ingredients Zileuton (USA: Zyflo) – not commercially available in many countries.
