Side effects Every drug has side effects – this is also the case with diuretics.The different groups of diuretics also have a different side effect profile, but some side effects are found in all drugs. In general, each drug carries the risk of developing hypersensitivity or allergy. This can lead to skin rashes, discomfort and … Side effects | Diuretics
What should be considered when weaning? A diuretic is a dehydrating drug that can be given for various diseases. Some of these diseases are serious and the use of the diuretic is well-considered by your doctor, so it is not recommended to discontinue a diuretic independently without consultation. For example, in the case of a … What should be considered when weaning? | Diuretics
Products Loop diuretics are commercially available as tablets, sustained-release capsules, and injection and infusion preparations. Torasemide and furosemide are the most commonly used in many countries today. Structure and properties Available loop diuretics are usually sulfonamide or sulfonylurea derivatives. Representatives without a sulfonamide structure also exist, for example, the phenoxyacetic acid derivative etacrynic acid. Effects … Loop Diuretics
Background Potassium ions play an important role in many biological processes, particularly in the generation of membrane and action potentials and electrical conduction in nerve cells and the heart. Potassium is 98% localized intracellularly. The primary active transporter Na+/K+-ATPase provides transport into cells. Two hormones maintain the deep extracellular potassium concentration. The first is insulin, … Hyperkalemia (High Potassium)
Background Potassium ions play an important role in many biological processes, particularly in the generation of membrane and action potentials and electrical conduction in nerve cells and the heart. Potassium is 98% localized intracellularly. The primary active transporter Na+/K+-ATPase provides transport into cells. Two hormones maintain the deep extracellular potassium concentration. The first is insulin, … Hypokalemia (Low Potassium)
Synonyms Lasix®, diuretic/diuretics, loop diuretic/loop diuretics, water tablets, diuretics Diuretics Torem Definition Furosemide is a chemical substance which, when it enters the body, causes increased urine excretion. The target of this drug is a specific ion transporter in the kidney. Introduction Furosemide belongs to the group of substances known as diuretics. In the kidney, a … Furosemide
Mode of action Furosemide inhibits a special transporter that occurs in a specific section of the tubule system. This transporter is a co-transport of sodium, potassium and chloride, which is located in the thick section of the ascending leg of the Henle loop. Due to the inhibition of the transporter, water reabsorption no longer takes … Mode of action | Furosemide
Dosage Usually the substance furosemide is taken in tablet form. The dose is 20 – 40 mg and can be repeated after 6 – 8 hours if necessary. In hospital, Furosemide can also be administered as a short infusion. The dosage here is also 20 – 40 mg. Side effects Due to the water being … Dosage | Furosemide
Products Bumetanide was commercially available in tablet form (Burinex, off label). It was approved in many countries in 1974. Structure and properties Bumetanide (C17H20N2O5S, Mr = 364.4 g/mol) is a white crystalline powder that is practically insoluble in water. Effects Bumetanide (ATC C03CA02) is diuretic with rapid onset and short duration of action. Indications Oedema … Bumetanide
What is an alkalosis? Every human being has a certain pH value in the blood, which should guarantee the functions of the cells and maintain the body function. In healthy people, this pH value is between 7.35 and 7.45 and is regulated by buffer systems in the blood. If this pH value exceeds 7.45, one … Alkalosis
Diagnosis The diagnosis can be made by a physician using a so-called blood gas analysis (BGA), in which pH, standard bicarbonate, base deviation, partial pressures and O2 saturation are measured. The following values indicate alkalosis: Furthermore, the determination of chloride excretion in urine can be diagnostically valuable. In metabolic alkalosis, which is caused by vomiting … Diagnosis | Alkalosis
How is alkalosis treated? The treatment again distinguishes between respiratory and metabolic alkalosis. If necessary, the patient can be sedated if the panic attack does not subside on its own. In any case, the patient should be sedated so that he/she no longer hyperventilates and breathing can normalise. This is done by substituting NaCl (in … How is alkalosis treated? | Alkalosis
