Pathogenesis (disease development) Bowen disease is an intraepidermal carcinoma in situ (literally, “cancer in situ”) of the skin. Histologically, atypical dyskeratotic cells are seen. Queyrat’s erythroplasia is considered Bowen’s disease of the transitional mucosa. It is also a carcinoma in situ. In the pathogenesis, infection with HPV type 16 is of great importance. Etiology (Causes) … Bowen’s Disease: Causes
2nd order laboratory parameters – depending on the results of the history, physical examination, etc. – for differential diagnostic clarification Small blood count Differential blood count Bacteriology: nasopharyngeal swab, (possibly nasal or throat swab) [cultural detection is reliable only within two weeks]. Pathogen detection by PCR (dry swab; material: tracheal secretion, bronchoalveolar lavage (BAL; method … Pertussis (Whooping Cough): Test and Diagnosis
Inguinal hernia – colloquially called inguinal hernia – (synonyms: inguinal hernia; inguinal hernia; ICD-10-GM K40.-: hernia inguinalis) is a hernia of the viscera in the region of the inguinal canal. Inguinal hernia is the most common type of hernia. A distinction can be made between a direct (medial) and an indirect (lateral) inguinal hernia, with … Inguinal Hernia: Symptoms, Causes, Treatment
Medical history (history of illness) is an important component in the diagnosis of anorexia nervosa (anorexia). Family history Are there any mental illnesses (e.g., eating disorder, depression) in your family that are common? Social history What is your profession? Is there any evidence of psychosocial stress or strain due to your family situation? How can … Anorexia Nervosa: Medical History
Endocrine, nutritional, and metabolic diseases (E00-E90). Obesity* * (obesity). Skin and subcutaneous (L00-L99) Cellulitis* /* * Cardiovascular system (I00-I99) Chronic venous insufficiency* /* * (venous insufficiency). Phlebitis* (inflammation of the veins) Stasis eczema* * Congestive heart failure* /* * Deep vein thrombosis* (TBVT) – occlusion of a leg vein by a thrombus. Lymphedema* /* * … Calf Swelling: Or something else? Differential Diagnosis
Congenital malformations, deformities, and chromosomal abnormalities (Q00-Q99). EAST syndrome (synonym: SeSAME syndrome) – genetic disorder with autosomal recessive inheritance characterized by cerebral spasms, sensorineural hearing loss, ataxia (disturbance of movement coordination and postural innervation), retardation (delayed development), intellectual deficit, and electrolyte disturbances (hypokalemia, metabolic alkalosis (metabolic alkalosis), hypomagnesemia/magnesium deficiency); age of manifestation: Infancy, neonatal period … Potassium Deficiency (Hypokalemia): Or something else? Differential Diagnosis
Psyche – Nervous System (F00-F99; G00-G99). Acute stress disorder Adjustment Disorder Burnout syndrome Post-traumatic stress disorder (PTSD)
A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body weight, height; further: Inspection (viewing). Skin, mucous membranes and sclerae (white part of the eye). Examination of the abdomen (abdomen) Percussion (tapping) of the abdomen Meteorism (flatulence): hypersonoric tapping sound. Attenuation of tapping sound … Sorbitol Intolerance: Examination
Dehydroepiandrosterone (DHEA; more specifically 5,6-didehydroepiandrosterone, also known as androstenolone or androst-5-en-3β-ol-17-one, as well as prasterone) is a weak male sex hormone (steroid hormone) produced in the adrenal cortex (zona reticularis). The formation of DHEA is stimulated here by adrenocorticotropic hormone (ACTH), which is secreted by the pituitary gland. In women, DHEA is additionally synthesized (20-30%) … Dehydroepiandrosterone (DHEA Hormone)
2nd order laboratory parameters – depending on the results of the history, physical examination and obligatory laboratory parameters – for differential diagnostic clarification. Small blood count [septic arthritis (inflammatory joint disease)/osteomyelitis (bone marrow inflammation): leukocytes ↑] Inflammatory parameters – CRP (C-reactive protein) [septic arthritides/osteomyelitis: CRP ↑]Note: Inflammatory parameters may not be elevated or only slightly … Hip Pain (Coxalgia): Test and Diagnosis
Obligatory medical device diagnostics. Conventional radiograph of the thorax (chest; radiographic thorax) in two planes [rib fractures; pleural effusion?, pneumothorax (entry of air into pleural space)?] Optional medical device diagnostics – depending on the results of the history, physical examination, laboratory diagnostics and obligatory medical device diagnostics – for differential diagnostic clarification. Computed tomography of … Rib Fracture: Diagnostic Tests
The following are the most important diseases or complications that may be contributed to by gliomas: Cardiovascular system (I00-I99). Venous thromboembolism (VTE; occlusion of a blood vessel by a detached blood clot). Neoplasms – tumor diseases (C00-D48). Hemorrhage into the tumor Psyche – nervous system (F00-F99; G00-G99) Affective disorders (mood disorders) Epilepsy (seizures) Cognitive disorders … Gliomas: Consequential Diseases
