Products Ticagrelor is commercially available in the form of film-coated tablets (Brilique). The active ingredient was approved in many countries in 2011. In 2018, additional meltable tablets were registered. Structure and properties Ticagrelor (C23H28F2N6O4S, Mr = 522.6 g/mol) is a cyclopentyltriazolopyrimidine without a thienopyridine structure. Ticagrelor is directly active. It has an active metabolite but, … Ticagrelor
Products Donepezil is commercially available in tablet and oral tablet form (Aricept, Aricept Evess, generics). It has been approved in many countries since 1997. Structure and properties Donepezil (C24H29NO3, Mr = 379.5 g/mol) is a piperidine derivative and a racemate. It is present in drugs as donepezil hydrochloride, a white crystalline powder that is soluble … Donepezil
Products Serotonin receptor antagonists are commercially available in the form of film-coated tablets, melting tablets, soft capsules, as syrups, and as infusion/injection preparations. This article refers to the setrone (5-HT3 receptor antagonists), which are used as antiemetics. The first agent from this group to be approved in the United States was ondansetron (Zofran) in 1991, … Serotonin Antagonists (Setrone)
Products Aripiprazole is commercially available in tablet, meltable tablet, syrup, solution for injection, and sustained-release injection suspension forms (Abilify, Abilify Maintena, generics). It has been approved in many countries since 2004 and in the United States since 2002. Generics entered the market in 2015. Also used is the prodrug aripiprazollauroxil (Aristada). Structure and properties Aripiprazole … Aripiprazole
Definition After a drug is ingested, it passes through the esophagus into the stomach and into the small intestine. There, the active ingredient must first be released from the dosage form. This is the prerequisite for it to be absorbed into the bloodstream via the cells of the mucosa. The dosage form thus exerts a … Release (Liberation)
Products Oxycodone is commercially available in the form of sustained-release tablets, capsules, melting tablets, as an injectable, and drops (including Oxycontin, Oxynorm, and generics). It has been used medicinally for decades. In the U.S., it is also used as a fix in combination with other analgesics such as acetaminophen (e.g., Percocet). Oxycodone is also available … Oxycodone: Drug Effects, Side Effects, Dosage and Uses
