meulengracht's disease

Paracetamol: Drug Effects, Side Effects, Dosage and Uses

Products Paracetamol is commercially available in the form of tablets, film-coated tablets, melting tablets, effervescent tablets, as granules, drops, syrups, suppositories, soft capsules, and infusion solution, among others (e.g., Acetalgin, Dafalgan, Panadol, and Tylenol). Paracetamol was not approved until the 1950s (Panadol, Tylenol), although it was developed in the 19th century. It has been registered … Paracetamol: Drug Effects, Side Effects, Dosage and Uses

Phenobarbital

Products Phenobarbital is commercially available in tablet form and as a solution for injection (aphenylbarbit, phenobarbital Bichsel). It was approved in many countries in 1944. Luminal has been off the market in many countries since late August 2011. Barbexaclone (maliasin), a fixed combination of phenobarbital and L-propylhexedrine, is also no longer available. Structure and properties … Phenobarbital

Glucuronidation

Definition Glucuronidation refers to an intracellular metabolic reaction in which an endogenous or exogenous substrate is conjugated to glucuronic acid. The organism thereby makes the substrates more water soluble so that they can be rapidly excreted in the urine. Glucuronidation belongs to phase II metabolism (conjugations). UDP: uridine diphosphate UGT: UDP-glucuronosyltransferase Enzymes involved Glucuronidation is … Glucuronidation

Paracetamol Suppositories

Products Paracetamol is available in suppository form from several suppliers (e.g., Panadol, Acetalgin, Ben-u-ron, Dafalgan, Tylenol). Available dosages include 80, 125, 250, 300, 350, 500, 600, and 1000 mg. Paracetamol suppositories are used primarily in pediatrics, but they can also be given to adults. Structure and properties Paracetamol (C8H9NO2, Mr = 151.2 g/mol) exists as … Paracetamol Suppositories

Meulengracht disease

Synonyms Meulengracht disease Gilbert-Meulengracht disease Gilbert syndrome Definition – What is Meulengracht’s disease? Meulengracht’s disease (Gilbert-Meulengracht’s disease, Gilbert syndrome) is a harmless disease caused by a congenital metabolic disorder of the liver. The disease is inherited from parents to children. Due to a gene mutation, bilirubin, the breakdown product of the red blood cells, is … Meulengracht disease

What can be the accompanying symptoms of Meulengracht’s disease? | Meulengracht disease

What can be the accompanying symptoms of Meulengracht’s disease? Meulengracht’s disease is a relatively harmless disease that rarely manifests itself through symptoms. Patients may suffer from abdominal pain, which is mainly perceived as an unpleasant feeling of pressure in the right upper abdomen. In addition, indigestion, nausea and flatulence may occur. Other symptoms are depressive … What can be the accompanying symptoms of Meulengracht’s disease? | Meulengracht disease

Treatment and therapy | Meulengracht disease

Treatment and therapy Meulengracht’s disease cannot be cured in principle, as the metabolic disorder is genetically inherited and congenital. In most cases, those affected manage well even without treatment and do not require therapy. In severe cases, the symptoms and gastrointestinal complaints can be treated with medication, although the side effects of the prescribed medication … Treatment and therapy | Meulengracht disease

Which drugs are involved in metabolization? | Meulengracht disease

Which drugs are involved in metabolization? In Meulengracht’s disease, the function of UDP-glucuronyltransferase is limited. Since the enzyme is important for the excretion of bilirubin as well as for the breakdown of other drugs, the disease can alter the effect of drugs and lead to undesired interactions. The drugs that are broken down by UDP-glucuronyltransferase … Which drugs are involved in metabolization? | Meulengracht disease

What effect does sport have on my disease and what kind of sport can I do? | Meulengracht disease

What effect does sport have on my disease and what kind of sport can I do? In general, people with Meulengracht’s disease are not physically impaired in any way and can practice any sport that suits them. Unfortunately, sport and physical activity do not contribute to a decrease in blood bilirubin levels. However, regular exercise … What effect does sport have on my disease and what kind of sport can I do? | Meulengracht disease