Tadalafil

Products Tadalafil is commercially available in the form of film-coated tablets (Cialis, Adcirca, generics). It has been approved in many countries since 2004. Generics were registered in 2016 and came on the market in 2019. This article is related to erectile dysfunction treatment. Structure and properties Tadalafil (C22H19N3O4, Mr = 389.4 g/mol) exists as a … Tadalafil

West Nile Virus

Symptoms The majority of patients (approximately 80%) are asymptomatic or develop only mild symptoms. Approximately 20% experience flu-like symptoms (West Nile fever) such as fever, headache, feeling sick, nausea, vomiting, muscle aches, and skin rashes. Other symptoms such as conjunctivitis, hepatitis, movement disorders or confusion are possible. Less than 1% develop neuroinvasive disease with meningitis, … West Nile Virus

Acupressure: Treatment, Effects & Risks

Problems with the neck, back pain, an incipient cold, headaches: for people “who have almost everything”, acupressure is often the right treatment method. Acupressure also opens up the possibility of effective self-treatment. Acupressure is part of Traditional Chinese Medicine (TCM). It originated in the court of the Chinese emperor more than 2,000 years ago, and … Acupressure: Treatment, Effects & Risks

Elosulfase Alfa

Products Elosulfase alfa was approved in the EU and US in 2014 and in many countries in 2016 as a concentrate for the preparation of an infusion solution (Vimizim). Structure and properties Elosulfase alfa is the recombinant form of the human enzyme -acetylgalactosamine-6-sulfatase. It is produced by biotechnological methods. Effects Elosulfase alfa (ATC A16AB12) replaces … Elosulfase Alfa

Dasatinib

Products Dasatinib is commercially available in the form of film-coated tablets (Sprycel). It has been approved in many countries since 2007. Generic versions were registered in 2020. Structure and properties Dasatinib (C22H26ClN7O2S, Mr = 488.0 g/mol) exists as a white powder that is insoluble in water. It is an aminopyrimidine derivative. Effects Dasatinib (ATC L01XE06) … Dasatinib

Alectinib

Products Alectinib was approved in capsule form in Japan in 2014, in the United States in 2015, and in many countries in 2017 (Alecensa). Structure and properties Alectinib (C30H34N4O2, Mr = 482.6 g/mol) is present in the drug product as alectinib hydrochloride, a white to yellow-white powder. It has an active metabolite (M4). Effects Alectinib … Alectinib

Home Remedies for Sore Muscles

Those who overdo it with sports or pursue unaccustomed strenuous activities often get a painful bill the following day. A sore muscle is not threatening from a medical point of view, but it is still extremely unpleasant. The good old home remedies are often a boon in this case and work at least as well … Home Remedies for Sore Muscles

Encorafenib

Products Encorafenib was approved in capsule form in the United States and EU in 2018 and in many countries in 2019 (Braftovi). Structure and properties Encorafenib (C22H27ClFN7O4S, Mr = 540.0 g/mol) exists as a white powder that is somewhat soluble in water only at low pH. Effects Encorafenib (ATC L01XE46) has antitumor and antiproliferative properties. … Encorafenib

Sonidegib

Products Sonidegib was approved in many countries in 2015 in capsule form (Odomzo). Structure and properties Sonidegib (C26H26F3N3O3, Mr = 485.5 g/mol) is present in the drug as sonidegib diphosphate. It is a biphenyl carboxamide. Effects Sonidegib (ATC L01XX48) has antitumor and antiproliferative properties. The effects are due to inhibition of the Hedgehog signaling pathway … Sonidegib

Peginterferon Alfa-2A

Products Peginterferon alfa-2a is commercially available as an injectable (Pegasys). It has been approved in many countries since 2002. Structure and properties Peginterferon alfa-2a is a covalent conjugate of the recombinant protein interferon alfa-2a and a branched monomethoxy polyethylene glycol (PEG). It has a molecular mass of approximately 60 kDa and is derived from by … Peginterferon Alfa-2A

Peginterferon Alfa-2B

Products Peginterferon alfa-2b was commercially available as an injectable (PegIntron). It had been approved in many countries since 2002. Structure and properties Peginterferon alfa-2b is a covalent conjugate composed of the recombinant protein interferon alfa-2b and a monomethoxy polyethylene glycol (PEG). It has a molecular weight of approximately 31 kDa. Peginterferon alfa-2b is obtained from … Peginterferon Alfa-2B