Products Belatacept was approved in many countries in 2011 as a powder for the preparation of an infusion solution concentrate (Nulojix). Structure and properties Belatacept is a soluble fusion protein consisting of a modified extracellular domain of human cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and a fragment of the Fc domain of a human IgG1 antibody. … Belatacept
Products Immunosuppressants are commercially available in numerous dosage forms, for example, as creams, ointments, tablets, capsules, solutions, eye drops, and injectables. Structure and properties Within immunosuppressants, several groups can be identified. These include steroids such as the glucocorticoids, substances of microbiological origin such as ciclosporin and mycophenolate mofetil, derivatives of nucleic acids and their components … Immunosuppressants
Products Mycophenolate is commercially available in the form of enteric-coated film-coated tablets (Myfortic). It has been approved in many countries since 2002. Structure and properties Mycophenolate is the deprotonated form of mycophenolic acid (C17H20O6, Mr = 320.3 g/mol). It is present in the drug as mycophenolate sodium, a white crystalline powder that is highly soluble … Mycophenolate
Products Mycophenolate mofetil is commercially available in the form of film-coated tablets, capsules, as an injectable, and as a suspension (CellCept, generics). It has been approved in many countries since 1995. Structure and properties Mycophenolate mofetil (C23H31NO7, Mr = 433.5 g/mol) exists as a white crystalline powder and is practically insoluble in water. It is … Mycophenolate Mofetil
Mycophenolic acid is a drug that belongs to the immunosuppressant class of drugs. It was the first characteristic antibiotic to be researched in its mode of action on cell growth and division. It has been considered a reliable drug for about 85 years and is now frequently prescribed in the field of organ transplantation. What … Mycophenolic Acid: Effects, Uses & Risks
