Nafarelin

Products Nafarelin is commercially available as a nasal spray (Synrelina). It has been approved in many countries since 1992. Structure and properties Nafarelin (C66H83N17O13, Mr = 1322.5 g/mol) is an agonist derivative and analog of gonadotropin-releasing hormone (GnRH). It is present in the drug as nafarelin acetate. It is a decapeptide that is administered nasally … Nafarelin

GnRH Analogs

Products GnRH analogs are commercially available in many countries in the form of injectables, implants, and nasal sprays, among others. The first agent to be approved was goserelin (Zoladex) in 1990. Structure and properties GnRH analogs are synthetically produced derivatives of gonadotropin-releasing hormone (GnRH, LHRH) produced in the hypothalamus. GnRH is a decapeptide and has … GnRH Analogs

Nasal Sprays

Products Nasal sprays are very widely used and there are many different products on the market, which are approved drugs or medical devices (see below). Nasal sprays are also manufactured in pharmacies. Structure and properties Nasal sprays are solutions, emulsions, or suspensions intended for spraying into the nasal cavities. They may contain one or more … Nasal Sprays

Hirsutism: Excessive Hair Growth

Definition Increased body and facial hair in women corresponding to the male hair type due to androgen-induced conversion of vellus hair to terminal hair. Symptoms Excessive and altered hair growth (thick and pigmented) on the face, chest, abdomen, legs, buttocks, and back Acne Deeper voice Increased muscle mass Decrease in breast size Androgenetic alopecia Views … Hirsutism: Excessive Hair Growth