Products Nesiritide was commercially available in many countries as a powder for the preparation of an infusion solution (Noratak) and had been approved since 2003. Because of a new study of 7141 patients that failed to show a difference between nesiritide and placebo, the product was withdrawn from the market on Dec. 31, 2011 (O’Connor … Nesiritide
Products Indapamide is commercially available as tablets and capsules alone in sustained-release formulations (Fludex SR, generic) and in combination with the ACE inhibitor perindopril (Coversum N Combi, generic). A fixed combination of perindopril, indapamide, and amlodipine is also available (Coveram plus). Indapamide was developed in the 1970s and has been approved in many countries since … Indapamide
Stem plant Convallariaceae, lily of the valley. Medicinal drug Convallariae herba – lily of the valley herb: the aerial parts of the L. collected at flowering time (PH 4) – no longer officinal. Preparations Discontinued powder Ingredients Cardiac glycosides of the cardenolide type: convallatoxin. Effects Positively inotropic Diuretic: natriuretic, kaliuretic Economizes the work of the … Lily of the Valley Health Benefits
Products The fixed combination of the neprilysin inhibitor sacubitril with valsartan was approved in the United States, the EU, and many countries in 2015 in the form of film-coated tablets (Entresto). The combination is also referred to as LCZ696. Structure and properties Sacubitril (C24H29NO5, Mr = 411.5 g/mol) is an ester prodrug that is hydrolyzed … Sacubitril
