Products Xipamide is not currently registered or commercially available in many countries. In Germany and Austria, it is available in tablet form (Aquaphor, Aquaphoril, generics). Structure and properties Xipamide (C15H15ClN2O4S, Mr = 354.8 g/mol) has a sulfonamide structure and is structurally related to the thiazides, but acts from the blood side. It exists as a … Xipamide
Products Chlortalidone is commercially available in tablet form (combination products). It has been approved in many countries since 1967. This article refers to the monopreparations. Hygroton (Novartis) was discontinued in many countries in 2014. Structure and properties Chlortalidone (C14H11ClN2O4S, Mr = 338.77 g/mol) is a racemate. It exists as a white to yellowish white powder … Chlortalidone
Products Metolazone is commercially available in tablet form as a generic product (Metolazone Galepharm). The original Zaroxolyn is no longer available. Structure and properties Metolazone (C16H16ClN3O3S, Mr = 365.8 g/mol) is a quinazoline sulfonamide that is sparingly soluble in water. It is structurally related to the thiazides. Effects Metolazone (ATC C03BA08) has diuretic and thiazide-like … Metolazone
Products Indapamide is commercially available as tablets and capsules alone in sustained-release formulations (Fludex SR, generic) and in combination with the ACE inhibitor perindopril (Coversum N Combi, generic). A fixed combination of perindopril, indapamide, and amlodipine is also available (Coveram plus). Indapamide was developed in the 1970s and has been approved in many countries since … Indapamide
