Eculizumab

Products Eculizumab is commercially available as a concentrate for the preparation of an infusion solution (Soliris). It was approved in many countries in January 2010. Structure and Properties Eculizumab is a monoclonal antibody produced by recombinant DNA technology in NSO cell lines. It is composed of two heavy and two light chains of amino acids … Eculizumab

Bacterial Meningitis

Symptoms Typical symptoms of bacterial meningitis include high fever, severe headache, and neck stiffness. However, these symptoms do not necessarily all have to be present. The disease may be accompanied by nausea, vomiting, skin rash, petechiae, sensitivity to light, and clouding of consciousness, among other symptoms. The infection can lead to blood poisoning and other … Bacterial Meningitis

Ravulizumab

Products Ravulizumab was approved in the United States in 2018, in the EU in 2019, and in many countries in 2020 as a concentrate for the preparation of an infusion solution (Ultomiris). Structure and properties Ravulizumab is an IgG2/4K monoclonal antibody produced by biotechnological methods. Effects Ravulizumab (ATC L04AA43) binds to complement protein C5, inhibiting … Ravulizumab

Meningococcus

Symptoms Meningococcus can cause a life-threatening meningitis, called meningococcal meningitis, and blood poisoning, called meningococemia. The three typical symptoms of meningitis include fever, severe headache and neck stiffness. Other possible symptoms include nausea, vomiting, photophobia, and neurological disorders such as confusion. In infants and young children, symptoms may be absent or difficult to recognize. Sepsis … Meningococcus