Products No drugs containing benznidazole are on the market in many countries. Rochagan or Radanil are not approved in many countries. Structure and properties Benznidazole (C12H12N4O3, Mr = 260.2 g/mol) is a nitroimidazole and an acetamide. The compound was originally developed at Roche and launched in the 1970s. Effects Benznidazole (ATC P01CA02) has antiparasitic properties. … Benznidazole
Products No finished drug products containing nifurtimox are on the market in many countries. Lampit is not approved in many countries. Structure and properties Nifurtimox (C10H13N3O5S, Mr = 287.3 g/mol) is a nitrofuran derivative. Effects Nifurtimox (ATC P01CC01) has antiparasitic properties. The effects are due to the formation of free radicals. Indications For the treatment … Nifurtimox
Symptoms Possible symptoms of African trypanosomiasis (sleeping sickness) in the first stage include: Nodule or ulcer on the skin at the bite site (trypanosome chancre). Feeling sick, fatigue, weight loss. Fever with chills Headache, joint pain Skin rash Swollen lymph nodes Organ diseases (eg, heart, liver, spleen). In the first stage, trypanosomes are in the … Trypanosomiasis