Nitroglycerin Patch

Products Nitroglycerin has been approved in many countries since 1981 in the form of a transdermal patch (Nitroderm, others). Structure and properties Nitroglycerin or glycerol trinitrate (C3H5N3O9, Mr = 227.1 g/mol) is an organic nitrate. It is nitrated glycerol. Nitroglycerin exists as an oily liquid and is explosive if not stabilized. Synthesis Effects Nitroglycerin (ATC … Nitroglycerin Patch

Nitroglycerin Ointment

Products Rectogesic ointment is approved in many countries (some countries: Rectiv). Nitroglycerin ointments are also used in a higher concentration for transdermal treatment of angina (2%). This article refers to rectal administration for anal fissure. Structure and properties Nitroglycerin or glycerol trinitrate (C3H5N3O9, Mr = 227.1 g/mol) is nitrated glycerol. Pure nitroglycerin is explosive and … Nitroglycerin Ointment

Explosives Precursors

Products Many of the chemicals involved are available in pharmacies and drugstores. Caution is advised when selling them. Suspicious transactions should be reported by specialists to the Federal Office of Police (fedpol). In many countries, legislation is currently being adapted to regulate access to precursors for private individuals and to make their misuse as difficult … Explosives Precursors

Menstrual Cramps

Symptoms The most common symptoms include cramping or dull abdominal pain. In addition, numerous other symptoms may occur, such as headache, menstrual migraine, back pain, pain in the legs, loss of appetite, nausea and vomiting, diarrhea, weakness, dizziness, flushing of the skin, flushing, sleep disturbances, mood swings, depression, irritability, and nervousness. The symptoms first appear … Menstrual Cramps

Nitric Acid

Products Nitric acid is available in pharmacies and drugstores in various concentrations. Structure and properties Nitric acid (HNO3, Mr = 63.0 g/mol) exists as a clear to nearly colorless liquid with a pungent odor that is miscible with water. It may turn yellowish in color. Various concentrations exist. These include: Fuming nitric acid: from about … Nitric Acid

Spasmolytics

Products Spasmolytics are commercially available in the form of tablets, suppositories, and injectables, among others. In many countries, scopolamine butylbromide is among the best-known representatives. Structure and properties Spasmolytics are often derived from the tropane alkaloids atropine and scopolamine from nightshade plants or from the benzylisoquinoline papaverine from the opium poppy. Effects Spasmolytics have spasmolytic … Spasmolytics

Bioavailability

Definition and properties When we take a tablet or capsule, it contains a defined amount of an active pharmaceutical ingredient. Usually, the full dose does not enter the bloodstream. Some active ingredients are not fully released from the dosage form (liberation), others are only partially absorbed from the intestine (absorption), and some are metabolized in … Bioavailability

Tendon Disorders

Symptoms Disease of the tendons or tendon sheaths often manifests as dull or stabbing pain, usually on one side and with movement, strain, or pressure. Other complaints include weakness, limited range of motion, and an audible crunching sound. The wrists and forearms are often affected. At a later stage, the pain may also be present … Tendon Disorders

Sapropterin

Background Phenylalanine is an essential amino acid that is not produced by the human organism itself. Phenylalanine ingested with food is produced by the enzyme phenylalanine hydroxylase and its cofactor 6-tetrahydrobiopterin (6-BH4) metabolized to tyrosine. Phenylketonuria is an autosomal recessive disorder caused by insufficient activity of phenylalanine hydroxylase, resulting in elevated blood phenylalanine levels, i.e., … Sapropterin

Nitroglycerin

Definition Nitroglycerin is a prescription drug with the active ingredient glycerol trinitrate (also called nitroglycerin) and is used as a mono-preparation. Application Nitroglycerin is used for acute attacks of angina pectoris. These are heart attacks caused by an undersupply of oxygen to the heart muscle. If an attack of angina pectoris is feared or already … Nitroglycerin

Side effects | Nitroglycerin

Side effects The following adverse drug reactions may occur when taking nitroglycerin: Headaches Tiredness Swindle Visual disorders Flush syndrome (reddening of the skin with a feeling of heat) Blood pressure drop during erection Slight pulse acceleration Nausea Vomiting Collapse The following drugs can cause undesirable or even dangerous interactions with nitroglycerin: Vasodilators Calcium antagonists Beta … Side effects | Nitroglycerin