Amsacrine

Products Amsacrine is commercially available as an infusion preparation (Amsidyl). It has been approved in many countries since 1993. Structure and properties Amsacrine (C21H19N3O3S, Mr = 393.5 g/mol) is an aminoacridine derivative. Effects Amsacrine (ATC L01XX01) has antineoplastic properties. The effects are due to inhibition of topoisomerase II. As a result, DNA synthesis is blocked. … Amsacrine

Sunitinib

Products Sunitinib is commercially available in capsule form (Sutent). It has been approved in many countries since 2006. Structure and properties Sunitinib (C22H27FN4O2, Mr = 398.5 g/mol) is present in the drug as sunitinibmalate, a yellow to orange powder that is soluble in water. It is an indolin-2-one and pyrrole derivative. It has an active … Sunitinib

Hydroxycarbamide

Products Hydroxycarbamide is commercially available in the form of capsules (Litalir, generics). It has been approved in many countries since 1995. Structure and properties Hydroxycarbamide (CH4N2O2, Mr = 76.1 g/mol) is a hydroxylated urea (-hydroxyurea). It exists as a white, crystalline, hygroscopic powder that is readily soluble in water. Effects Hydroxycarbamide (ATC L01XX05) is cytostatic. … Hydroxycarbamide

Oral Mucositis

Symptoms Oral mucositis manifests as redness, swelling, pain, a burning sensation, aphthae, a white to yellowish coating, sores, ulceration, bleeding, and bad breath, among other symptoms. The tongue and gums may also be affected. The discomfort may increase in association with eating. Sores can be so painful that food intake is limited, which can lead … Oral Mucositis

Gold

Products Gold compounds are commercially available (worldwide) in the form of capsules and injection solutions (e.g., Ridaura, Tauredon), among others. They are rarely used medicinally today. Structure and properties Elemental gold (Latin: aurum, abbreviation: Au, M. r = 96.97 g/mol, atomic number 79) is a chemical element and a lustrous noble metal with a yellow … Gold

Lenvatinib

Products Lenvatinib was approved in many countries in 2015 in capsule form (Lenvima). In 2017, Kisplyx capsules were also approved. Structure and properties Lenvatinib (C21H19ClN4O4, Mr = 426.9 g/mol) is present in the drug as lenvatinib mesilate, a white to pale reddish-yellow powder that is sparingly soluble in water. It is a quinoline and carboxamide … Lenvatinib