Products Methotrexate is commercially available as a solution for parenteral use and in tablet form. See also under methotrexate prefilled syringe (low-dose). Structure and properties Methotrexate (C20H22N8O5, Mr = 454.44 g/mol) is a dicarboxylic acid that exists as a yellow to orange crystalline powder that is virtually insoluble in water. Methotrexate was developed as a … Methotrexate: Drug Effects, Side Effects, Dosage and Uses
Background The “gluten” protein is a protein mixture found in many grains such as wheat, rye, barley, and spelt. Its high content of the amino acids glutamine and proline makes gluten resistant to breakdown by digestive enzymes in the intestines, which contributes to the inflammatory response. Gluten has elastic properties and is therefore an important … Celiac
Products Dacomitinib was approved in the US in 2018 and in the EU and many countries in 2019 in film-coated tablet form (Vizimpro). Structure and properties Dacomitinib (C24H25ClFN5O2, Mr = 469.9 g/mol) is present in the drug product as dacomitinib monohydrate, a white to pale yellow powder. Effects Dacomitinib (ATC L01XE47) has antitumor and antiproliferative … Dacomitinib
Products Tioguanine is commercially available in tablet form (Lanvis). It has been approved in many countries since 1973. Structure and properties Tioguanine (C5H5N5S, Mr = 167.2 g/mol) is a 6-thiol analog of guanine. Effects Tioguanine (ATC L01BB03) has cytotoxic properties as a purine antimetabolite. Indications For the treatment of acute myeloid leukemia. Other indications include … Tioguanin
Loosestrife is a wild perennial found in our latitudes. Its importance as a medicinal plant is generally little known. Occurrence and cultivation of the loosestrife. The plant can grow more than one meter high. Its flowering period is from June to August. Loosestrife (Lysimachia vulgaris), also known as field loosestrife, is a plant of moist … Loosestrife: Applications, Treatments, Health Benefits
Products Docetaxel is commercially available as an infusion preparation (Taxotere, generics). It was approved in many countries in 1996 as a second taxane after paclitaxel (Taxol). Structure and properties Docetaxel (C43H53NO14, Mr = 807.9 g/mol) is present in the drug as docetaxel trihydrate, a white powder that is practically insoluble in water. The lipophilic drug … Docetaxel
Products Probiotics for the oral cavity are commercially available as lozenges and, in some countries, as chewing gum. They are marketed as dietary supplements. Structure and properties The products contain millions of viable bacteria found in healthy pharyngeal and oral flora. These include: DSM 17938 and ATCC PTA 5289. BLIS K12 Effects The bacteria attach … Probiotics Lozenges
Products Metronidazole is commercially available in various dosage forms for systemic and topical therapy. This article refers to the film-coated tablets (Flagyl and generic). The drug has been approved in many countries since 1960. Structure and properties Metronidazole (C6H9N3O3, Mr = 171.2 g/mol) is a derivative of imidazole substituted with a nitro group, a methyl … Metronidazole
Products Benzylpenicillin (penicillin G) is commercially available as an injectable (Penicillin Grünenthal). Structure and properties Benzylpenicillin (C16H18N2O4S, Mr = 334.4 g/mol) is present in the drug as benzylpenicillin sodium, a white crystalline powder that is very soluble in water. Other salts are also available. Benzylpenicillin is not acid stable, has low absorption, and therefore can … Benzylpenicillin
Products Fludarabine is commercially available as an injection/infusion preparation (generic, original: Fludara). It was approved in the United States in 1991 and in many countries in 1995. Structure and properties Fludarabine (C10H12FN5O4, Mr = 285.2 g/mol) or 9-β-D-arabinosyl-2-fluoroadenine is present in drugs as fludarabine phosphate, a white, crystalline, hygroscopic powder that is sparingly soluble in … Fludarabine
Products Tetracyclines are commercially available in many countries in the form of tablets, capsules, and injection and infusion solutions, among others. This article refers primarily to peroral therapy. The first tetracycline, chlortetracycline (aureomycin, Lederle), was discovered in the 1940s during screening of soil samples under the direction of Benjamin Minge Duggar and became commercially available … Tetracycline: Drug Effects, Side Effects, Dosage and Uses
Products Chlorambucil is commercially available in the form of film-coated tablets (Leukeran). It has been approved in many countries since 1957. Structure and properties Chlorambucil (C14H19Cl2NO2, Mr = 304.2 g/mol) is an aromatic nitrogen-lost derivative. It exists as a white crystalline powder that is practically insoluble in water. The effects are due to the active … Chlorambucil
