Bone densitometry is used to assess the risk of osteoporosis as well as bone fractures. Different measurement methods allow an assessment of bone strength and structure by determining the calcium salt content in the examined bone. What is bone densitometry? Schematic representation of the density of healthy bone and bone with osteoporosis. Click to enlarge. … Bone Densitometry: Treatment, Effect & Risks
Bone tissue remodeling corresponds to bone remodeling that occurs permanently within bone tissue. Bones are adapted to current loading conditions by the remodeling processes of osteoclasts and osteoblasts. Excessive bone remodeling characterizes Paget’s disease. What is bone tissue remodeling? Bone tissue remodeling corresponds to bone remodeling that occurs permanently within bone tissue. Bone tissue damage … Bone Tissue Remodeling (Bone Remodeling): Function, Tasks, Role & Diseases
Important note: Paget’s disease is used synonymously for two different diseases. On the one hand, Paget’s disease is a disease from the field of gynecology and cancer. Paget’s disease from the field of gynecology is a malignant tumor (cancer) of the mammary duct in the area of the female nipple. Synonyms in a broader sense … Paget’s disease
Symptoms As already described above, a distinction is made between an asymptomatic and a symptomatic course of the disease. An asymptomatic course means that the disease was diagnosed as a so-called “random finding” and no main place of manifestation can be determined. Patients with a symptomatic course of the disease have pain, especially in the … Symptoms | Paget’s disease
General information An involvement of the skull bones is usually first noticed by a deformation or increase in size of the skull, since this becomes visible on the head quite early due to the lack of fat and connective tissue. Patients report, for example, that hats or helmets no longer fit them properly. X-ray If … General information | Paget’s disease
Bone biopsy It is relatively rare for a tissue sample of the bone (bone biopsy) to be taken. This diagnostic method is only necessary if, after CT and MRI examinations, bone metastases or Paget’s sarcoma are still suspected. The latter is a malignant bone tumor (osteosarcoma), which develops from degenerated osteoblasts in one percent of … Bone biopsy | Paget’s disease
Bisphosphonates for therapy The following bisphosphonates are currently approved for the treatment of Paget’s disease: The choice of the form of therapy, and thus in particular the drug therapy of Paget’s disease, must always be determined individually with regard to the substances administered, the dosage and the duration of the therapy. Combinations of the various … Bisphosphonates for therapy | Paget’s disease
The fibula is one of the two bones of the lower leg. This belongs to the long bones. What is the fibula? The fibula is a tubular lower leg bone. Together with the tibia (shin bone), to which it attaches on the outside, it forms the human lower leg. The fibula is thinner in circumference … Fibula: Structure, Function & Diseases
What are aggressive breast cancers? Some breast cancers are classified as rather aggressive, either because they respond poorly to therapy or because they have a tendency to metastasize after a short time. However, the exact classification of breast cancers is very complicated and is based on various prognostically relevant factors. Therefore, general statements should only … What are aggressive breast cancers? | Subtypes of breast cancer
Synonyms in a broader sense Breast carcinoma, breast-Ca, invasive ductal breast carcinoma, invasive lobular breast carcinoma, inflammatory breast carcinoma, Paget’s disease, carcinoma in situ Is breast cancer equal to breast cancer? In principle, there are many different types of breast cancer, depending on the cell type from which the cancer originally develops. However, some of … Subtypes of breast cancer
Van Nuys Prognostic Index In order to be able to assess whether there is a risk of recurrence after DCIS therapy, the Van Nuys Prognostic Index was established: In this index, various characteristics are taken into account and evaluated with a point system, including the size of the area, the degree of differentiation (grading) and … Van Nuys Prognostic Index | Subtypes of breast cancer
Special form of carcinoma in situ A special form of DCIS is Paget’s carcinoma, also called Paget’s disease of the nipple. If the DCIS is located near the nipple, it can spread to the skin of the nipple and lead to inflammation with secretion and swelling. Paget’s disease of the nipple should not be confused … Special form of carcinoma in situ | Subtypes of breast cancer