Products Carbidopa is used in combination with levodopa in tablet form. In addition to the original Sinemet, generic versions are also available. Carbidopa has been approved in many countries since 1973. Structure and properties Carbidopa (C10H14N2O4, Mr = Mr = 226.2 g/mol) is present in drugs as carbidopa monohydrate, a white crystalline powder that is … Carbidopa
Effects Aphrodisiac Medical indications To promote sex drive or potency. Erectile dysfunction in men “Hypoactive Sexual Desire Disorder” (decreased sexual drive). Active ingredients Use v.a. in erectile dysfunction: phosphodiesterase-5 inhibitors increase blood flow to the corpus cavernosum of the penis and act only during sexual stimulation: Sildenafil (Viagra) Tadalafil (Cialis) Vardenafil (Levitra) Prostaglandins must be … Aphrodisiacs
Products Cabergoline is commercially available in tablet form (Cabaser, Dostinex). It has been approved in many countries since 1995. Structure and properties Cabergoline (C26H37N5O2, Mr = 451.6 g/mol) is a dopaminergic ergoline derivative. It exists as a white crystalline powder that is practically insoluble in water. Effects Cabergoline (ATC N04BC06) has dopaminergic properties and reduces … Cabergoline
Products Tolcapone is commercially available in the form of film-coated tablets (Tasmar). It has been approved in many countries since 1997. Structure and properties Tolcapone (C14H11NO5, Mr = 273.2 g/mol) exists as a yellow, odorless, non-hygroscopic, crystalline powder. It is a nitrobenzophenone. Effects Tolcapone (ATC N04BX01) affects the pharmacokinetics of levodopa. The effects are due … Tolcapon
Effects Decarboxylase inhibitors inhibit decarboxylase, which metabolizes levodopa to dopamine. They are used exclusively in combination with levodopa to treat Parkinson’s disease. Their effect is limited to the periphery because they hardly cross the blood–brain barrier. Decarboxylase inhibitors thus allow more or less selective degradation of levodopa to dopamine in the central nervous system and … Decarboxylase Inhibitor
Products In many countries, no drugs containing trimetazidine are commercially available. In other countries, film-coated tablets of modified release and dropper solutions are available (e.g., Vastarel), among others. Structure and properties Trimetazidine (C14H22N2O3, Mr = 266.3 g/mol) is a piperazine derivative. It is present in the drug as trimetazidine dihydrochloride. Effects Trimetazidine (ATC C01EB15) has … Trimetazidine
Products Asenapine is commercially available in the form of sublingual tablets (Sycrest). It was approved in many countries in 2012. In the United States, it has been registered since 2009. Structure and properties Asenapine (C17H16ClNO, Mr = 285.8 g/mol) is present in the drug as asenapine maleate. It belongs to the class of dibenzooxepin pyrroles. … Asenapine
Effects The majority of antiparkinsonian drugs are directly or indirectly dopaminergic. Some are anticholinergic in action. Indications Parkinson’s disease, including drug-induced Parkinson’s disease in some cases. Drug treatment Overview of drug therapy: 1. dopaminergic agents Levodopa is a precursor of dopamine and is considered the most important and effective pharmacotherapy for PD. Combining it with … Antiparkinsonian
Symptoms Hoarseness describes a change in voice quality. The voice may sound smoky, noisy, strained, raspy, trembling, or weak. Causes The larynx is made up of cartilage, muscle, and mucosa. It is innervated by the vagus nerve. If any of these elements is disturbed, hoarseness may result. 1. inflammation (laryngitis): Viral infections, for example, a … Hoarseness Causes and Remedies
Flexible dosage By dividing, the fixed dose of tablets can be changed, which increases flexibility. This is because a dose reduction may be necessary for children, for patients with renal insufficiency, for drug interactions, or for altered drug metabolism. Tablets are also divided for economic reasons. For example, the duration of therapy may be doubled … Divisibility of Tablets
Risperdal® Consta® is a preparation from the group of atypical neuroleptics with the active ingredient risperidone. It is available in powder and solution form and is used to prepare a soluble suspension for intramuscular injection. Thanks to a special preparation of the active ingredient, Risperdal® Consta® is a long-term neuroleptic with a duration of action … Risperdal Consta
Contraindications Risperdal® Consta® must not be given in cases of hyperprolactinaemia, i.e. when there are elevated levels of the hormone prolactin in the blood. This excess of prolactin can be caused by a tumor of the pituitary gland (so-called prolactinoma). Particular caution is advised when taking Risperdal® Consta® in patients with Parkinson’s disease and severe … Contraindications | Risperdal Consta
