Pharyngitis (Sore Throat)

Pharyngitis: Description The term pharyngitis actually stands for inflammation of the pharyngeal mucosa: the mucous membrane lining the throat is inflamed. Doctors distinguish between two forms of the disease – acute pharyngitis and chronic pharyngitis: Acute pharyngitis: An acutely inflamed pharynx is very common and usually accompanies a cold or flu infection. Pharyngitis: Symptoms The … Pharyngitis (Sore Throat)

Azithromycin

Products Azithromycin is commercially available in the form of film-coated tablets, powder for preparation of a suspension, and granules (Zithromax, generic). Furthermore, a granule for the preparation of a sustained-release oral suspension is available (Zithromax Uno). Eye drops have also been released in some countries. Azithromycin has been approved in many countries since 1992. Structure … Azithromycin

Benralizumab

Products Benralizumab was approved as a solution for injection in the United States in 2017 and in the EU and many countries in 2018 (Fasenra). Structure and properties Benralizumab is a humanized and afucosylated IgG1κ antibody with a molecular mass of 150 kDa. It is produced by biotechnological methods. Omission of the fucose in the … Benralizumab

Inhaled Glucocorticoids

Effects Glucocorticoids (ATC R03BA02) have anti-inflammatory, antiallergic, and immunosuppressive properties. The effects are based on binding to intracellular receptors, resulting in an influence on protein expression. In addition, glucocorticoids also exert extragenomic effects. All agents are lipophilic (virtually insoluble in water) and thus enter cells well across the cell membrane. Indications For the treatment of … Inhaled Glucocorticoids

Macitentan

Products Macitentan is commercially available in the form of film-coated tablets (Opsumit). It was approved in the United States in October 2013 and in many countries in 2014. Macitentan was launched as a successor to bosentan (Tracleer) as it loses patent protection. Structure and properties Macitentan (C19H20Br2N6O4S, Mr = 588.3 g/mol) is a brominated pyrimidine … Macitentan

Hoarseness Causes and Remedies

Symptoms Hoarseness describes a change in voice quality. The voice may sound smoky, noisy, strained, raspy, trembling, or weak. Causes The larynx is made up of cartilage, muscle, and mucosa. It is innervated by the vagus nerve. If any of these elements is disturbed, hoarseness may result. 1. inflammation (laryngitis): Viral infections, for example, a … Hoarseness Causes and Remedies

Streptococcal Angina

Symptoms A typical strep throat starts suddenly with sore throat and swallowing pain and an inflammation of the throat. The tonsils are inflamed, red, swollen, and coated. Further, fever occurs while cough is absent. The cervical lymph nodes are painfully enlarged. Possible accompanying symptoms include headache, muscle aches, abdominal pain, chills, a scarlet-like rash, nausea, … Streptococcal Angina

Sore Throat

Symptoms Sore throat manifests as an inflamed and irritated throat lining and pain when swallowing or at rest. The palatine tonsils may also be inflamed, swollen, and coated. Possible accompanying symptoms include mucus production, cough, hoarseness, fever, headache, runny nose, eye irritation, feeling sick, and fatigue. Causes The most common cause of sore throat is … Sore Throat

Triamcinolone Acetonide Nasal Spray

Products Triamcinolone acetonide nasal sprays have been approved in many countries since 1996 and are commercially available as propellant-free metered-dose sprays (Nasacort, Nasacort Allergo, Suspension). Structure and properties Triamcinolone acetonide (C24H31FO6, Mr = 434.5 g/mol) is a white crystalline powder that is practically insoluble in water. It is a lipophilic and potent derivative of triamcinolone. … Triamcinolone Acetonide Nasal Spray

Epiglottitis: Inflammation of the Epiglottis

Symptoms Epiglottitis manifests itself in the following symptoms, which appear suddenly: Fever Dysphagia Pharyngitis Salivation Muffled, throaty voice Difficulty breathing and breathing sounds (stridor). Poor general condition Unlike pseudocroup, cough is rare Most affected are children between 2-5 years, but the disease can also occur in adults. Thanks to good vaccination coverage since the 1990s, … Epiglottitis: Inflammation of the Epiglottis