Shadow Drugs

Shadow Medication Regulatory-approved drugs are well documented with patient and professional information and scientific research. They have a brand name and are managed, promoted, and distributed by a company. They are available in pharmacies and drugstores and can be ordered from wholesalers or directly from the company. In addition to these official drugs, there is … Shadow Drugs

Sildenafil

Products Sildenafil is commercially available in the form of film-coated tablets and as a solution for injection (Viagra, Revatio, generics). It has been approved in many countries since 1998. Generics went on sale July 22, 2013, and the patent expired June 21. Pfizer launched auto-generic sildenafil Pfizer, identical to the original, back in May. In … Sildenafil

Amyl Nitrite

Products Amyl nitrite is commercially available in the form of ampoules (Amyle Nitrite Inhalant USP). The product, available in many countries, is imported from abroad and is not officially approved as a drug. Amyl nitrite is included in the Federal Office of Public Health‘s antidote list and must be stocked in hospitals for the treatment … Amyl Nitrite

Prostate Enlargement Causes and Treatment

Symptoms Benign hyperplasia of the prostate is a typical and chronic age-related condition in men. Approximately 50% of men over 50 and 80% of men over 80 are affected. The incidence and symptoms increase with age. Age is therefore the most important risk factor. The clinical symptoms are also called “benign prostatic syndrome”, because the … Prostate Enlargement Causes and Treatment

Nicorandil

Products Nicorandil is commercially available in tablet form (Dancor). It has been approved in many countries since 1993. Structure and properties Nicorandil (C8H9N3O4, Mr = 211.2 g/mol), like nitroglycerin, is an organic nitrate. It is a combination of the vitamin nicotinamide with an ethyl nitrate. Effects Nicorandil (ATC C01DX16) has vasodilator, antihypertensive, and cardioprotective properties. … Nicorandil

Diffuse Esophageal Spasm

Symptoms Diffuse esophageal spasm manifests as seizure-like pain behind the breastbone (chest pain) and difficulty swallowing. The pain may radiate to the arms and jaw, similar to angina. Other possible symptoms include shortness of breath, cramping and burning. The duration of attacks varies, ranging from seconds to minutes. They are often triggered by food intake, … Diffuse Esophageal Spasm

Organic Nitrates

Products Nitrates are commercially available in the form of chewable capsules, transdermal patches, infusion preparations, ointment, sustained-release tablets, sustained-release capsules, and sprays. As the first representative, nitroglycerin was already produced in the 19th century and used for the treatment of angina pectoris. Nitrates are thus among the oldest synthetic drugs. Structure and properties Organic nitrates … Organic Nitrates

Apomorphine

Products Uprima sublingual tablets (2 mg, 3 mg) for erectile dysfunction are no longer marketed in many countries. The marketing authorization was not renewed by Abbott AG in 2006. Commercial reasons were cited, probably attributed to competition from phosphodiesterase-5 inhibitors (e.g., sildenafil, Viagra). It is also possible that a post-marketing study had played a role, … Apomorphine

Alprostadil Cream

Products Alprostadil cream Vitaros was approved in many countries in 2016. It is an export approval. In some countries, it is marketed as Virirec. Structure and properties Alprostadil (C20H34O5, Mr = 354.5 g/mol) exists as a white to slightly yellowish crystalline powder that is practically insoluble in water. The substance structurally corresponds to natural prostaglandin … Alprostadil Cream

Nitroglycerin Capsules

Products Nitroglycerin is commercially available in many countries in the form of chewable capsules (Nitroglycerin Streuli). The active ingredient was produced and used medicinally as early as the 19th century. Structure and properties Nitroglycerin or glycerol trinitrate (GTN, C3H5N3O9, Mr = 227.1 g/mol) is an organic nitrate. It is nitrated glycerol. Nitroglycerin exists as an … Nitroglycerin Capsules

Nitroglycerin Patch

Products Nitroglycerin has been approved in many countries since 1981 in the form of a transdermal patch (Nitroderm, others). Structure and properties Nitroglycerin or glycerol trinitrate (C3H5N3O9, Mr = 227.1 g/mol) is an organic nitrate. It is nitrated glycerol. Nitroglycerin exists as an oily liquid and is explosive if not stabilized. Synthesis Effects Nitroglycerin (ATC … Nitroglycerin Patch

Nitroglycerin Ointment

Products Rectogesic ointment is approved in many countries (some countries: Rectiv). Nitroglycerin ointments are also used in a higher concentration for transdermal treatment of angina (2%). This article refers to rectal administration for anal fissure. Structure and properties Nitroglycerin or glycerol trinitrate (C3H5N3O9, Mr = 227.1 g/mol) is nitrated glycerol. Pure nitroglycerin is explosive and … Nitroglycerin Ointment