Products Elotuzumab was approved in the United States in 2015 and in the EU and Switzerland in 2016 as a powder for the preparation of an infusion solution (Empliciti). Structure and properties Elotuzumab is a humanized IgG1 monoclonal antibody with a molecular weight of 148.1 kDa. It is produced by biotechnological methods. Effects Elotuzumab (ATC … Elotuzumab
Effects Carbapenems (ATC J01DH) are bactericidal against aerobic and anaerobic Gram-positive and Gram-negative pathogens. Effects are based on binding to penicillin-binding proteins (PBP) and inhibition of bacterial cell wall synthesis, resulting in bacterial dissolution and death. Imipenem, the first representative of the drug group, is degraded by the renal enzyme dehydropeptidase-I (DHP-I). It is therefore … Carbapeneme
Products Enalapril is commercially available in tablet form (Reniten, generics). It has been approved in many countries since 1984. The active ingredient is also combined fixed with hydrochlorothiazide. Structure and properties Enalapril (C20H28N2O5, 376.45 g/mol) is present in drugs as enalapril maleate, a white powder that is sparingly soluble in water. Enalapril is the prodrug … Enalapril: Drug Effects, Side Effects, Dosage and Uses
Pneumonia or pneumonia is mostly triggered in the colder season, such as winter or autumn. In this case, mainly bacteria, fungi and viruses play a significant role in transmission. But also by coughing and sneezing of other people it can come to the droplet infection and thus to pneumonia. What is pneumonia? Infographic on the … Pneumonia: Causes, Symptoms & Treatment
Tracheoesophageal fistula connects the trachea to the esophagus, causing symptoms such as coughing fits and food aspiration. The phenomenon is usually congenital and in this case is usually associated with malformation of the trachea and esophagus. Treatment is surgical. What is a tracheoesophageal fistula? Fistulas are tubular connections between hollow organs or the body surface … Tracheoesophageal Fistula: Causes, Symptoms & Treatment
Symptoms Middle East respiratory syndrome (MERS) manifests as a respiratory illness with flu-like symptoms such as: Fever, chills Cough, sore throat Muscle and joint pain Shortness of breath Digestive problems such as nausea and diarrhea The disease can lead to severe pneumonia, ARDS (Acute Respiratory Distress Syndrome), septic shock, renal failure and multi-organ failure. It … MERS
Products The MMR vaccine is commercially available as an injectable. Vaccination has been recommended in many countries since the 1980s. Some preparations also contain the chickenpox vaccine (= MMRV vaccine). Effects MMR (ATC J07BD52) is a live vaccine consisting of attenuated measles, mumps, and rubella viruses. These childhood diseases can cause significant complications and numerous … MMR Vaccination
Esophageal stricture, or esophageal stenosis, is one of the less dangerous complications. However, if left untreated, not only can it itself become dangerous, but it can also be a sign of other diseases. In this respect, esophageal stenosis requires immediate medical treatment in any case. What is esophageal stricture? The human digestive system begins in … Esophageal Stricture: Causes, Symptoms & Treatment
Products Isatuximab was approved in many countries, in the EU, and in the United States in 2020 as a concentrate for the preparation of an infusion solution (Sarclisa). Structure and properties Isatuximab is a chimeric monoclonal antibody derived from IgG1. It is produced by biotechnological methods. The molecular mass is approximately 148 kDa. Effects Isatuximab … Isatuximab
Symptoms Possible symptoms include high fever, pneumonia, deep pulse, headache, muscle pain, cough, and shortness of breath. Furthermore, skin rashes, indigestion, lower abdominal pain, and diarrhea may occur. After an attack on the respiratory tract, various organs such as the heart, liver, and digestive tract may be secondarily affected. The disease was first described by … Parrot Disease
The rue captivates by its yellow flowers, which are usually found in large numbers. Precisely because of its great popularity as an ornamental plant and likewise as a medicinal herb, the plant had to be placed under conservation to prevent complete extinction. The rue offers many possibilities to be used as a medicinal plant and … Sweet Rue: Applications, Treatments, Health Benefits
DNA damage can be caused by a variety of causes such as UV radiation. This damage is then repaired by a variety of DNA repair mechanisms so that subsequent protein biosynthesis, which is necessary fϋr all processes in the body, can proceed smoothly. What is DNA repair? DNA consists of a double strand and is … DNA Repair: Function, Tasks, Role & Diseases
