Products The fixed combination Pylera with the active ingredients bismuth, metronidazole, and tetracycline was approved in many countries in 2017 in the form of hard capsules. In some countries, it was available much earlier, for example, in the United States since 2006. This treatment is the so-called bismuth quadruple therapy (“BMTO”), which was developed by … Bismuth, Metronidazole, Tetracycline
Proton pump inhibitors (PPI for proton pump inhibitors) are stomach-protecting medications. They used to require a prescription, but now PPIs with the active ingredients pantoprazole and omeprazole are available over the counter in pharmacies for self-medication of heartburn and acid regurgitation. In about 30 percent of the population, stomach acid flows back into the esophagus … Proton Pump Inhibitors for Heartburn
Products Itraconazole is commercially available in capsule form and as an oral solution (Sporanox, generic). It has been approved in many countries since 1992. Sporanox infusion concentrate is no longer available. Structure and properties Itraconazole (C35H38Cl2N8O4, Mr = 705.6 g/mol) exists as a white powder that is practically insoluble in water. It belongs to the … Itraconazole
Products Clopidogrel is commercially available in tablet form (Plavix, generics). It has been approved in the United States since 1997 and in many countries and the EU since 1998. Clopidogrel is also combined with acetylsalicylic acid fixed (DuoPlavin). Structure and properties Clopidogrel (C16H16ClNO2S, Mr = 321.82 g/mol) is a thienopyridine derivative and a prodrug. It … Clopidogrel: Drug Effects, Side Effects, Dosage and Uses
Products Pantoprazole is commercially available in the form of enteric-coated tablets and has been approved in many countries since 1997 (Pantozol, generic). Less commonly used are the granules and the injectable. Structure and properties Pantoprazole (C16H15F2N3O4S, Mr = 383.37 g/mol) is a benzimidazole derivative and a racemate. In tablets, it is present as sodium salt … Pantoprazole
Products Proton pump inhibitors (PPIs) are commercially available in many countries in the form of film-coated tablets, MUPS tablets, capsules, as granules for preparation of an oral suspension, and as injectable and infusion preparations. The first active ingredient from this group to be approved in many countries was omeprazole (Antra, Losec), developed by Astra in … Proton Pump Inhibitors
Drug gastric protection Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used for acute and long-term treatment of painful and inflammatory conditions. Active ingredients used include, for example, diclofenac, acetylsalicylic acid, ibuprofen, naproxen, and mefenamic acid. However, their use is limited by adverse effects that affect the upper digestive tract and are due to inhibition of prostaglandin … Stomach Protection
Products Dabigatran is commercially available in capsule form (Pradaxa). It has been approved in many countries since 2012. It was first approved in 2008. Structure and properties Dabigatran (C25H25N7O3, Mr = 471.5 g/mol) is present in drugs as mesilate and in the form of the prodrug dabigatran etexilate, which is metabolized in the organism by … Dabigatran
Products The fixed combination containing 81 mg acetylsalicylic acid and 20 mg esomeprazole was approved in many countries in June 2012 in capsule form (Axanum). In the EU, the drug has been registered since 2011. The amount of acetylsalicylic acid contained is less than in Aspirin cardio and generics, which usually contain 100 mg of … Acetylsalicylic Acid and Esomeprazole
Products Ponatinib is commercially available in film-coated tablet form (Iclusig). It was approved in the EU in 2013 and in many countries in 2014. Structure and properties Ponatinib (C29H27F3N6O, Mr = 532.6 g/mol) is present in the drug as ponatinib hydrochloride, a white to yellow powder whose water solubility decreases with increasing pH. It is … Ponatinib
Synonyms in a broader sense Proton pump inhibitors PPI Gastric acid blocker Nexium® MUPS Agopton® Lansogamma® Lansoprazole-ratiopharm Antra® MUPS Omegamma® Omep® Omeprazole STADA Ulcozol® Pariet® Pantozol®. Pantoprazole®. Rifun® Definition Proton pump inhibitors (short: PPI;= proton pump inhibitors) are very effective drugs for the treatment of stomach acid-related complaints such as heartburn, esophagitis or stomach ulcers. … Proton pump inhibitor (PPI)
Application of proton pump inhibitors Heartburn is an unpleasant symptom that can occur in different forms. Mild forms can usually be treated by changing one’s lifestyle and taking antacids (drugs that bind stomach acid). However, if acid-induced stomach complaints and heartburn occur relatively frequently, you should seek medical clarification of the cause. You could be … Application of proton pump inhibitors | Proton pump inhibitor (PPI)
