Physiological background Itch results from activation of specialized afferent unmyelinated C fibers in the skin. These fibers are anatomically identical to those that conduct pain but differ in function and stimulus transmission to the brain. They contain a number of receptors such as histamine receptors, PAR-2, endothelin receptor, and TRPV1, and mediators such as histamine, … Itch
ExplanationDefinition Lyrica ® originally comes from the pharmacotherapeutic group of drugs against epilepsy (antiepileptic drugs). The active substance name is Pregabalin. In pain therapy, the main area of application is neuropathic pain (nerve pain). Lyrica ® is a protected trade name of the company Pfizer. Chemical name Pregabalin ((S)-3-(aminomethyl)-5-methylhexanoic acid) Fields of application Neuropathic pain … Lyrica®
Side effects Lyrica® is in most cases a well tolerated drug. The most common side effects are mild to moderate drowsiness and drowsiness (>1/10). In addition (>1/100 and < 1/10): Apart from undesirable effects of the active ingredient pregabalin, Lyrica®, like any drug, can trigger an allergic reaction. This is particularly manifested by swelling, e.g. … Side effects | Lyrica®
Duration of the side effect The occurrence and duration of side effects vary significantly from patient to patient. The side effects listed in the package insert can also be attributed to the interaction with other drugs or to the corresponding underlying disease. Normally, the side effects last for the duration of the therapy and only … Duration of the side effect | Lyrica®
Contraindications Who should not take Lyrica®? Patients with an allergy to the active ingredient pregabalin or other drug components. Patients with hereditary galactose intolerance Patients with lapp lactase deficiency Patients with glucose-galactose malabsorption. Price Since there is always talk of cost pressure in the health care system, I think it is important to know the … Contraindications | Lyrica®
Products Gabapentin is commercially available in the form of capsules and film-coated tablets (Neurontin, generic). It has been approved in many countries since 1994. Pfizer launched pregabalin (Lyrica) as its successor in 2004. Structure and properties Gabapentin (C 9 H 17 NO 2 , M r = 171.2 g/mol) is structurally a GABA analog and … Gabapentin: Drug Effects, Side Effects, Dosage and Uses
Products Lamotrigine is commercially available as tablets and dispersible or chewable tablets (Lamictal, generics). It has been approved in many countries since 1994. Vanillin is typically added to the tablets as a flavoring agent and saccharin as a sweetener. Structure and properties Lamotrigine (C9H7Cl2N5, Mr = 256.1 g/mol) is a chlorinated phenyltriazine derivative that was … Lamotrigine (Lamictal)
Symptoms Postherpetic neuralgia manifests as localizable and unilateral pain in the area that was affected by shingles, increased tenderness (allodynia1) and pruritus. The pain character is described as itchy, burning, sharp, stabbing, and throbbing, among others. The discomfort occurs even though the shingles has healed and can sometimes last for months and even years. The … Postherpetic Neuralgia
