Products Adalimumab is commercially available as a solution for injection (Humira). It was approved in the United States in 2002 and in many countries and the EU in 2003. Biosimilars are available in many countries. Structure and properties Adalimumab is a human IgG1 monoclonal antibody against TNF-alpha. It is composed of 1330 amino acids and … Adalimumab Effects and Side Effects
Symptoms Psoriasis is a chronic inflammatory, benign, and noninfectious skin disease. It manifests as symmetrical (bilateral), sharply demarcated, bright red, dry, raised plaques covered by silvery scales. Typically affected areas are the elbows, knees, and scalp. Itching, a burning sensation and pain are other symptoms, and scratching further aggravates the condition. Psoriasis can also affect … Psoriasis Causes and Treatment
Products Apremilast is commercially available in the form of film-coated tablets (Otezla). It was approved in the United States in 2014 and in many countries and the EU in 2015. Structure and properties Apremilast (C22H24N2O7S, Mr = 460.5 g/mol) is a dioxoisoindole acetamide derivative. Effects Apremilast (ATC L04AA32) has immunomodulatory and anti-inflammatory properties. The effects … Apremilast
Products Leflunomide is commercially available in the form of film-coated tablets (Arava, generics). It has been approved in many countries since 1998. In 2011, generic versions went on sale in many countries. Structure and properties Leflunomide (C12H9F3N2O2, Mr = 270.2 g/mol) is an isoxazole carboxamide. It is a prodrug and is biotransformed in the intestine … Leflunomide
Introduction Both neurodermatitis and psoriasis are chronic inflammatory skin diseases that are accompanied by reddening and scaling of the skin. However, there are important differences in the development of the diseases and in their form of manifestation, which make different treatment necessary. An exact differentiation of the two diseases is therefore very important but not … Neurodermatitis and psoriasis – What is the difference?
What is psoriasis? Psoriasis vulgaris is a benign, chronic inflammatory, non-infectious skin disease. It is characterized by easily distinguishable, reddish patches, usually covered by whitish scales. The skin changes are mainly found on the extensor sides of the extremities (elbows, knees, possibly hairy scalp) and can be accompanied by itching as well as nail changes. … What is psoriasis? | Neurodermatitis and psoriasis – What is the difference?
Is it possible to get neurodermatitis and psoriasis simultaneously? A simultaneous occurrence of psoriasis and neurodermatitis is possible but very rare. There is no direct connection between the two diseases. The inflammatory factors, which play an important role in the development of psoriasis, are not involved in neurodermatitis. The same is true the other way … Is it possible to get neurodermatitis and psoriasis simultaneously? | Neurodermatitis and psoriasis – What is the difference?
Introduction The knee joint is generally very susceptible to injuries and complaints. Due to the high weight load caused by the body weight alone, as well as by stress in many sports, knee problems and acute knee pain are not uncommon. Acute pain often occurs suddenly and is usually triggered by overloading or an accident. … Acute knee pain
Accident causes Among the causes of acute knee pain directly caused by accidents are Below is a brief informative description of the respective clinical picture. – Articular effusion Hofftitis Free joint body Acute Baker cyst Hematoma in the knee Cruciate ligament rupture Torn meniscus Sideband rupture (inner/outer band) Broken bone Patellar luxation Runner’s knee An … Accident causes | Acute knee pain
