Products Atazanavir is commercially available in capsule form (Reyataz). It has been approved in many countries since 2004. Generic versions were registered in 2017. Structure and properties Atazanavir (C38H52N6O7, Mr = 704.9 g/mol) is present in drugs as atazanavir sulfate, a white to slightly yellow crystalline powder that is sparingly soluble in water. Effects Atazanavir … Atazanavir
Products Atorvastatin is commercially available in the form of film-coated tablets (Sortis, generic, auto-generic). It has been approved in many countries since 1997. Atorvastatin is also available as a fixed combination with ezetimibe; see Atorvastatin and Ezetimibe. Structure and Properties Atorvastatin (C33H35FN2O5, Mr = 558.64 g/mol) is present in drugs as atorvastatin calcium trihydrate, (atorvastatin)2– … Atorvastatin
Products and production Morphine drops are an aqueous dropping solution of morphine hydrochloride, usually in concentration 1% or 2%, maximum 4%. The concentration refers to the salt; the effective amount of morphine base is less. The drug is subject to strict control as an anesthetic and is available only on prescription. The morphine drops of … Morphine Drops
Products Levonorgestrel is commercially available as the so-called morning-after pill in tablet form (e.g., NorLevo, generics). It is available under a doctor’s care. Since 2002, it may also be sold in pharmacies for emergency contraception after structured professional counseling and dispensing documentation. Levonorgestrel is also contained in other hormonal contraceptives. These are tablets containing ethinyl … Levonorgestrel
Products Fosamprenavir is commercially available in the form of film-coated tablets (Telzir). It has been approved in many countries since 2005. Structure and properties Fosamprenavir (C25H36N3O9PS, Mr = 585.6 g/mol) is present in drugs as fosamprenavir calcium. It is a prodrug that is rapidly biotransformed in the intestinal mucosa to the active metabolite amprenavir. Amprenavir … Fosamprenavir
Products Saquinavir is commercially available in the form of film-coated tablets (Invirase). It has been approved in many countries since 1996 (United States: 1995). Structure and properties Saquinavir (C38H50N6O5, Mr = 670.8 g/mol) is present in the drug as saquinavir mesilate, a white, weakly hygroscopic powder that is practically insoluble in water. Effects Saquinavir (ATC … Saquinavir
P-glycoprotein P-glycoprotein (P-gp, MDR1) is a primary active efflux transporter with a molecular weight of 170 kDa, belonging to the ABC superfamily and consisting of 1280 amino acids. P-gp is the product of the -gene (formerly: ). P is for , ABC is for . Occurrence P-glycoprotein is found on various tissues of the human … P-Glycoprotein
Ritonavir is the name given to an HIV protease inhibitor. The drug is used to treat HIV infections such as AIDS. What is ritonavir? Ritonavir is the name given to an HIV protease inhibitor. The drug is used to treat HIV infections such as AIDS. Ritonavir is an active ingredient that belongs to the protease … Ritonavir: Effects, Uses & Risks
