Products Lovastatin is not commercially available in many countries. Structure and properties Lovastatin (C24H36O5, Mr = 404.5 g/mol) exists as a white crystalline powder that is insoluble in water. Effects Lovastatin is lipid-lowering. Indications Dyslipidemia
Products Mevastatin has never been marketed but has played an important role in the development of statins. Structure and properties Mevastatin (C23H34O5, Mr = 390.5 g/mol), the first statin, was identified as a natural product in 1973 at the Japanese pharmaceutical company Sanyko by Akira Endo during screening of thousands of mushroom extracts from. Effects … Mevastatin
Products Atorvastatin is commercially available in the form of film-coated tablets (Sortis, generic, auto-generic). It has been approved in many countries since 1997. Atorvastatin is also available as a fixed combination with ezetimibe; see Atorvastatin and Ezetimibe. Structure and Properties Atorvastatin (C33H35FN2O5, Mr = 558.64 g/mol) is present in drugs as atorvastatin calcium trihydrate, (atorvastatin)2– … Atorvastatin
