Introduction The so-called serotonin noradrenaline reuptake inhibitors (SNRI) are mainly drugs used in the treatment of depression. The most important active ingredients in this class of drugs are venlafaxine and duloxetine. The name refers to the ability of these drugs to exert their effect on both serotonin and noradrenalin levels in the central nervous system. … SNRI
Effect of SNRI As described above and as can be seen from the name, serotonin noradrenalin reuptake inhibitors (SNRI) inhibit the reuptake of serotonin and noradrenalin into the nerve cells. In order to understand this mechanism, one should consider the structure of a synapse, i.e. an interconnection point between two nerve cells. A synapse consists … Effect of SNRI | SNRI
When should SNRI not be given? SNRIs must not be used if an intolerance and allergic reaction to the active substance has occurred. The use of so-called MAOIs, the irreversible monoamine oxidase inhibitors, is also considered a strict contraindication.These are drugs used to treat depression or Parkinson’s disease. If taken at the same time or … When should SNRI not be given? | SNRI
SNRI during pregnancy Pregnancy and antidepressants are two closely interwoven topics, as numerous studies have shown that the incidence of depression is significantly higher among pregnant women and women in the puerperium than in the general population. The most important piece of advice regarding pregnancy during depression treatment is to tell your doctor that you … SNRI during pregnancy | SNRI
What should be considered when weaning? Patients treated with SNRI should not discontinue or change the dose without consulting their doctor. SNRI should never be stopped suddenly. This can lead to life-threatening side effects. These include symptoms such as fatigue, dizziness, headache, drowsiness or confusion, diarrhea, nausea, nervousness, agitation, or discomfort. Seizures are also possible … What should be considered when weaning? | SNRI
