Products In many countries, finished medicines containing cocaine are currently no longer commercially available. However, they can be prepared as an extemporaneous prescription in a pharmacy. Cocaine is subject to the Narcotics Act and requires an aggravated prescription, but it is not banned as a drug. It is also sold as an illegal narcotic on … Cocaine: Drug Effects, Side Effects, Dosage and Uses
Products Ondansetron is commercially available in the form of film-coated tablets, meltable tablets (lingual tablets), as a syrup, and as an infusion/injection preparation. In addition to the original Zofran, generic versions are also available. Ondansetron was introduced in 1991 as the first active ingredient from the group of 5-HT3 receptor antagonists was approved. Structure and … Ondansetron
Products Ketanserin is commercially available as a gel (Vulketan). It has been approved in many countries since 1995 and exclusively as a veterinary drug. In other countries, it is also available for human use as an antihypertensive. Structure and properties Ketanserin (C22H22FN3O3, Mr = 395.4 g/mol) is a quinazolinone derivative. Ketanserin hydrogenotartrate is used in … Ketanserin
Products MDEA is one of the narcotics and banned substances in many countries. It is not commercially available. MDEA was first mentioned in the 1970s in the books of Alexander Shulgin. Structure and properties Methylenedioxyethylamphetamine (C12H17NO2, Mr = 207.3 g/mol) is a 3,4-methylenedioxy derivative of an -ethylated amphetamine. It is structurally closely related to ecstasy … MDEA (Methylenedioxyethylamphetamine)
Products Fluvoxamine is commercially available in the form of film-coated tablets (Floxyfral). It has been approved in many countries since 1983. Structure and properties Fluvoxamine (C15H21F3N2O2, Mr = 318.33 g/mol) is present in drugs as fluvoxamine maleate, a white, odorless, crystalline powder that is sparingly soluble in water. Effects Fluvoxamine (ATC N06AB08) has antidepressant properties. … Fluvoxamine
Products In many countries, there are no finished medicines containing amineptine on the market. Amineptin is one of the narcotics and requires an aggravated prescription. It was withdrawn from the market in France and other European countries in 1999 (Survector, Servier). Structure and properties Amineptine (C22H27NO2, Mr = 337.5 g/mol) belongs to the tricyclic antidepressants. … Amineptin
Products Triptans are mainly taken in the form of film-coated tablets and melting tablets. Some are also available as subcutaneous injectable solutions and nasal sprays. Suppositories are no longer commercially available in many countries. Sumatriptan (Imigran) was the first agent in this group to be approved in the United States in 1992 and in many … Triptans: Drug Effects, Side Effects, Dosage and Uses
Products Tricyclic antidepressants are commercially available in many countries in the form of dragées, tablets, capsules, and drops. The first representative, imipramine, was developed at Geigy in Basel. Its antidepressant properties were discovered in the 1950s by Roland Kuhn at the psychiatric clinic in Münsterlingen (Thurgau). Imipramine was approved in many countries in 1958. Structure … Tricyclic Antidepressants
Products Clomipramine is commercially available as sustained-release tablets and coated tablets (Anafranil). It has been approved in many countries since 1966 (originally Geigy, later Novartis). The injection and infusion preparations are no longer marketed. Structure and properties Clomipramine (C19H23ClN2, Mr = 314.9 g/mol) is present in drugs as clomipramine hydrochloride, a white to pale yellow … Clomipramine
Prof. Susan L. Lucak, MD, is associate director of the Center for Intestinal Dysfunction and a gastroenterologist at Columbia-Presbyterian Medical Center in New York. She also holds a chair in clinical medicine at Columbia University’s College of Physicians and Surgeons in New York. Dr. Lucak: Irritable bowel syndrome is the most common gastrointestinal disorder in … Expert Interview on Irritable Bowel Syndrome
Products Diphenhydramine is commercially available in tablet, drop, and gel forms (e.g., Benocten, Nardyl Sleep, Fenipic plus), among others. It is also known as Benadryl in some countries. Diphenhydramine was developed in the 1940s. It is also a component of the active ingredient dimenhydrinate. Structure and properties Diphenhydramine (C17H21NO, Mr = 255.4 g/mol) is present … Diphenhydramine
Products Most antidepressants are commercially available in the form of film-coated tablets. In addition, oral solutions (drops), meltable tablets, dispersible tablets, and injectables are also available, among others. The first representatives were developed in the 1950s. It was discovered that the antituberculosis drugs isoniazid and iproniazid (Marsilid, Roche) had antidepressant properties. Both agents are MAO … Antidepressants
