How does clobazam work? Clobazam is an active substance from the benzodiazepine group. These substances increase the affinity of the body’s own neurotransmitter GABA (gamma-aminobutyric acid) to its binding site on the GABAA receptor. In the presence of clobazam, the GABA effect on the receptor increases. More chloride ions flow into the nerve cell, making … Clobazam: Effects and Side Effects
How fexofenadine works Fexofenadine acts as a selective inhibitor of docking sites of the body’s own messenger substance histamine – the so-called histamine H1 receptors. In this way, the active ingredient prevents allergic reactions. The messenger substance histamine has a variety of functions in the body. For example, it serves as a messenger between nerve … Fexofenadine: Effects, Uses, Side Effects
How cetirizine works As a so-called H1 antihistamine, cetirizine blocks the docking sites (H1 receptors) of the body’s own messenger substance histamine – a substance that occurs everywhere in the body and is involved in normal concentrations in important processes such as the immune response, the production of stomach acid and the regulation of sleep. … Cetirizine: Effects, Applications, Side Effects
How furosemide works Like all loop diuretics, furosemide is a so-called “high-ceiling diuretic”. With such diuretics, water excretion can be increased in proportion to the dose over a wide dose range. This is not possible with other diuretics (e.g. thiazides). Here, a maximum effect sets in after a certain dose, which cannot be intensified by … Furosemide: Effects, Applications, Side Effects
What effect has valerian? The healing power of the plant is mainly in the essential oil of the rhizome and roots. It is composed of a variety of effective components. The main ingredient of valerian oil is bornyl acetate. Other ingredients include: β-caryophyllene Valeranone Valerenal Bornyl isovalerate Valerenic acid It is known from clinical studies … Valerian: Effects and Side effects
How Bisacodyl works Bisacodyl is a “prodrug”, i.e. a precursor of the actual active substance. It is converted by the bacteria in the large intestine into the active form BHPM. This inhibits the absorption of sodium and water from the stool into the blood and promotes the release of water and electrolytes into the intestine. … Bisacodyl: Effects, Applications, Side Effects
What is Paxlovid? Paxlovid is a prescription medicine for covid-19 treatment. It currently has a provisional (conditional) approval for the European market. Paxlovid is one of the antiviral drugs. That is, it interferes with the ability of the coronavirus to replicate in the body. It can be taken in tablet form and consists of two … Paxlovid: Effects, Application, Side Effects
How sumatriptan works Triptans such as sumatriptan enter the brain via the blood and activate certain docking sites (receptors) for the nerve messenger serotonin (5-HT1 receptor) on the surface of nerve cells and blood vessels in the brain. This causes the blood vessels, which are dilated during an attack, to constrict and also results in … Sumatriptan: Effects, Uses, Side Effects
How does daridorexant work? Daridorexant is the first active ingredient approved in Europe from the group of orexin receptor antagonists. Orexins are messenger substances produced naturally in the body that influence our eating behavior and sleep patterns. If they bind to their receptor, we stay awake longer. Daridorexant blocks this receptor and thus has an … Daridorexant: Effects, Side Effects
How cisplatin works Cisplatin is an inorganic platinum-containing heavy metal compound. It is a so-called cytostatic drug: It inhibits DNA synthesis in cells by senselessly cross-linking the DNA strands. This means that the DNA information cannot be read or can only be read incorrectly. Cell division is thus inhibited – the cell perishes. Absorption, degradation … Cisplatin: Effects, Areas of Application, Side Effects
How valproic acid works Valproic acid interferes with neuronal events at various points in brain metabolism. It blocks voltage-dependent sodium channels and T-type calcium channels. In addition, it increases the concentration of the nerve messenger gamma-aminobutyric acid (GABA) by inhibiting its degrading enzymes. Glutamic acid, for example, is an excitatory neurotransmitter, while GABA is an … Valproic Acid: Effect, Side Effects
How Roxithromycin works Like all macrolide antibiotics, Roxithromycin also blocks bacterial protein synthesis. In this way, the growth and reproduction of bacteria is inhibited (bacteriostatic effect). Just like animal and human cells, bacterial cells also have genetic material (DNA) that serves as a blueprint for the proteins that fulfill numerous tasks in the cell. Roxithromycin … Roxithromycin: Effects, Areas of Application, Side Effects
