Diphenhydramine

Products Diphenhydramine is commercially available in tablet, drop, and gel forms (e.g., Benocten, Nardyl Sleep, Fenipic plus), among others. It is also known as Benadryl in some countries. Diphenhydramine was developed in the 1940s. It is also a component of the active ingredient dimenhydrinate. Structure and properties Diphenhydramine (C17H21NO, Mr = 255.4 g/mol) is present … Diphenhydramine

Chloral Hydrate

Products Chloral hydrate was approved in many countries in 1954 and is commercially available as a solution (Nervifene). Other products such as Medianox and chloraldurate are no longer available. Structure and properties Chloral hydrate (C2H3Cl3O2, Mr = 165.4 g/mol) is in the form of colorless, transparent crystals that are very soluble in water. It has … Chloral Hydrate

Zaleplon

Products Zaleplon was commercially available in capsule form (Sonata, 5 mg, 10 mg). It was approved in many countries in 1999. It was discontinued from distribution in April 2013. Structure and properties Zaleplon (C17H15N5O, Mr = 305.3 g/mol) is a pyrazolopyrimidine and exists as a white powder that is practically insoluble in water. It is … Zaleplon

Fibromyalgia Causes and Treatment

Symptoms Fibromyalgia is a chronic, noninflammatory disorder that manifests as pain throughout the body and is characterized by numerous other complaints. It is much more common in women than in men and usually first appears in middle age. Chronic, bilateral, diffuse pain. Muscle pain, pain in the limbs, back pain, joint pain, neck pain, headaches, … Fibromyalgia Causes and Treatment

The anaesthetic induction

Definition Anaesthesia induction is the process of preparing the patient for anaesthesia, an artificially induced state of unconsciousness and painlessness. These preparations follow a fixed scheme. The anaesthetic induction is followed by the anaesthetic continuation, during which this state of unconsciousness is maintained until the operation is finished and the patient can wake up from … The anaesthetic induction

Adverse Effects

Definition and examples Any pharmacologically active drug can also cause adverse drug reactions (ADRs). According to the WHO definition, these are harmful and unintended effects during intended use. In English, this is referred to as an (ADR). Typical adverse effects are: Headache, dizziness, sleep disturbance, fatigue, impaired reaction time. Gastrointestinal symptoms such as nausea, diarrhea, … Adverse Effects

Sleeping Pills: Intake and Side Effects

Sleeping pills (hypnotics) belong to the group of psychotropic drugs. They act in the brain and ensure a better sleep by adjusting certain control circuits. However, taking sleeping pills is often associated with side effects. That is why strong drugs are only available on prescription. Herbal sleep aids such as valerian, on the other hand, … Sleeping Pills: Intake and Side Effects

Psychotropic Drugs: Types, Effects, Indications, Dosage

Products Psychotropic drugs are commercially available, for example, in the form of tablets, melting tablets, dragées, capsules, drops, solutions and as injectables. The first psychotropic drugs were developed in the 1950s. Structure and properties Psychotropic drugs vary chemically, but groups with a common structure can be identified, for example, the benzodiazepines, the phenothiazines, and the … Psychotropic Drugs: Types, Effects, Indications, Dosage

Intoxicant

Products Legally, a distinction can be made between legal intoxicants (e.g., alcohol, nicotine) and prohibited substances (e.g., many hallucinogens, some amphetamines, opioids). Some substances, such as the opioids or the benzodiazepines, are used as drugs and are legally available with a doctor’s prescription. However, their use as intoxicants is not intended and is therefore referred … Intoxicant

Lorazepam

Products Lorazepam is commercially available as tablets, meltable tablets, and a solution for injection. In addition to the original Temesta, generics and a combination product with the sedative antihistamine diphenhydramine are also available (Somnium). Lorazepam has been approved in many countries since 1973. Structure and properties Lorazepam (C15H10Cl2N2O2, Mr = 321.2 g/mol) is a white … Lorazepam

Lormetazepam

Products Lormetazepam is commercially available in tablet form (Loramet). Both drugs have been approved in many countries since 1981. Noctamide is no longer marketed. Structure and properties Lormetazepam (C16H12Cl2N2O2, Mr = 335.18 g/mol) is an -methylated lorazepam (Temesta). It belongs to the 5-aryl-1,4-benzodiazepines. Effects Lormetazepam (ATC N05CD06) has antianxiety, sedative, sleep-inducing, anticonvulsant, and muscle relaxant … Lormetazepam