Not much is known about the causes of autosomal recessive lamellar ichthyosis. However, mutations have been found in the enzyme transglutaminase. Transglutaminase is responsible for the formation of the cell membrane in the stratum corneum cells. In the meantime, a second gene locus has been found, but what is encoded at this site is currently … Ichthyosis: Causes and Social Consequences
Structure of the skin The skin (cutis), with an area of about 2 m2 and accounting for 15% of body weight, it is one of the largest organs in humans. It consists of the epidermis (upper skin) and the dermis (leather skin) underneath. The outermost layer, the epidermis, is a keratinized, multilayered squamous epithelium without … Skin
Products Isotretinoin gel has been approved in many countries since 1994 (Roaccutan Gel, Germany: Isotrex Gel). Structure and properties Isotretinoin (C20H28O2, Mr = 300.4 g/mol) exists as a yellow to faint orange crystalline powder that is practically insoluble in water. Especially in solution, it is sensitive to air, heat, and light. Isotretinoin is a stereoisomer … Isotretinoin Gel
