Symptoms Drug-induced prolongation of the QT interval can rarely lead to severe arrhythmias. This is polymorphic ventricular tachycardia, known as torsade de pointes arrhythmia. It can be seen on the ECG as a wave-like structure. Due to the dysfunction, the heart cannot maintain blood pressure and can only pump insufficient blood and oxygen to the … Prolongation of the QT Interval
Products Paroxetine is commercially available as film-coated tablets and as a suspension (Deroxat, generic). It has been approved in many countries since 1993. Paroxetine is also marketed as Seroxat and Paxil in some countries. Slow-release paroxetine (CR) is not currently available in many countries. Structure and properties Paroxetine (C19H20FNO3, Mr = 329.4 g/mol) is present … Paroxetine
Products Thioridazine has been off the market in many countries since 2005 because of cardiac risks. Melleril and Mellerette tablets are out of commerce. In Germany and other countries, thioridazine remains on the market. Structure and properties Thioridazine (C21H26N2S2, Mr = 370.6 g/mol) is a phenothiazine derivative with a piperidinyl alkyl side chain. In drugs, … Thioridazine
The active substance thioridazine represents a neuroleptic. It can be used to treat schizophrenia and other mental illnesses. What is thioridazine? The active substance thioridazine represents a neuroleptic. It can be used to treat schizophrenia and other mental illnesses. The antipsychotic thioridazine is part of the group of active substances known as neuroleptics. From a … Thioridazine: Effects, Uses & Risks
Products Rolapitant was approved in the form of film-coated tablets in the United States in 2015, in the EU in 2017, and in many countries in 2018 (Varuby). Structure and properties Rolapitant (C25H26F6N2O2, Mr = 500.5 g/mol) is present in the drug as rolapitane hydrochloride, a white powder that is more soluble in water at … Rolapitant
