Introduction The respective dosage of Clexane® is selected according to the respective area of application. Important: The indicated dosages are only approximate values and must always be selected and adjusted by a physician according to the respective disease. Dosage The dose of Clexane® is determined according to body weight or the risk of disease or … Dosage of Clexane
Therapeutic dosage Clexane® is administered in therapeutic doses for diseases such as deep vein thrombosis, pulmonary embolism, atrial fibrillation or heart attacks. The therapeutic dosage is weight dependent and is calculated according to the formula 1 mg/kg. Thus, a woman with a body weight of 60 kg receives Clexane 60 mg (Clexane 0.6). If Clexane … Therapeutic dosage | Dosage of Clexane
Overdose The greatest danger of overdose of Clexane® is bleeding complications. These manifest themselves for example as nosebleeds (epistaxis), bloody urine (haematuria), bruises (haematomas) of the skin, small bleedings of the skin (petechiae) or bloody tarry stools (melena). Signs of hidden, invisible bleeding are a drop in blood pressure or certain laboratory changes (haemoglobin drop, … Overdose | Dosage of Clexane
Synonyms Enoxaparin, enoxaparin sodium, low molecular weight heparin, Lovenox® English = enoxaparin sodium, low molecular weight heparins (LMWH) The side effects of Clexane® are The main side effects that can occur with Clexane® administration are bleeding. Since Clexane® has a blood-thinning effect and inhibits coagulation, bleeding sources in the body are not or only insufficiently … Side effect of Clexane
Interactions Clexane® interact with a number of other drugs. On the one hand, the effect of Clexane® can be enhanced by certain substances, resulting in an increased tendency to bleed. On the other hand, the effect of Clexane® can be weakened, i.e. there is less bleeding due to less blood dilution. The effect of Clexane® … Interactions | Side effect of Clexane
Clexane® is the trade name of a drug with the active ingredient enoxaparin. This belongs to the group of low-molecular-weight heparins and is intended to inhibit blood coagulation by inhibiting the activity of a coagulation factor (factor Xa). Clexane® is used for the prophylaxis of thromboses, the treatment of thrombosis and pulmonary embolism and for … Clexane® during pregnancy
What are the side effects? The side effects of Clexane® correspond to the general side effects of the preparation. In addition there are a few special features that should be considered. If the risk-benefit ratio has been weighed well, the side effects are minor. A great advantage is that Clexane® does not cross the placental … What are the side effects? | Clexane® during pregnancy
Clexane during pregnancy Pregnancy is an exceptional situation for the maternal body. Both positive and negative effects of pregnancy are possible. A thrombophilic tendency during pregnancy can be considered a negative effect. This means that blood clots are more likely to form. In the case of other risk factors and existing underlying diseases a therapy … Clexane during pregnancy | Clexane
Synonyms Active ingredient: enoxaparin, enoxaparin sodium, synonyms in the broader sense: low molecular weight heparin, Lovenox® English: enoxaparin sodium, low molecular weight heparins (LMWH) Definition Clexane® belongs to the group of medicinal anticoagulants. These anticoagulants are divided into: Clexane® belongs to the group of low-molecular-weight heparins, which comprises various substances that differ from unfractionated heparin … Clexane
Dosage form Clexane® is administered depending on the indication: Clexane® must not be injected into the muscles (i.m., intramuscularly). – Thrombosis prophylaxis = subcutaneous injection (into subcutaneous fatty tissue) Thrombosis therapy = subcutaneous injection Non-suspension infarction (NSTEMI) /instable angina pectoris = subcutaneous injection Elevation myocardial infarction (STEMI) = first intravenous bolus administration, then subcutaneous injection … Dosage form | Clexane
Pharmacokinetics After subcutaneous injection of Clexane®, it enters the bloodstream where it reaches its average maximum activity level after three to five hours. Clexane® is broken down both in the liver (hepatic elimination) and in the kidney (renal elimination), with the majority being taken over by the liver. The plasma half-life – the time after … Pharmacokinetics | Clexane
As the name suggests, thrombosis prophylaxis is a therapeutic measure to prevent thrombosis. The danger of blood clots is in the further course of embolisms and heart attacks. What is thromboprophylaxis? A thrombosis is a blood clot (thrombus) that forms in the human vascular system or heart. Such a clot is formed by blood clotting. … Thromboprophylaxis: Treatment, Effects & Risks
