Products Legally, a distinction can be made between legal intoxicants (e.g., alcohol, nicotine) and prohibited substances (e.g., many hallucinogens, some amphetamines, opioids). Some substances, such as the opioids or the benzodiazepines, are used as drugs and are legally available with a doctor’s prescription. However, their use as intoxicants is not intended and is therefore referred … Intoxicant
Symptoms Possible symptoms of acute back pain include muscle aches, tension, stabbing pain, limited mobility, and stiffness. The pain may radiate down the leg (sciatic pain), and patients may be unable to stand up straight. While acute pain is comparatively treatable, chronic back pain poses a serious quality of life and mental health problem and … Back Pain Causes and Treatment
Physiological background Sweat is produced by millions of eccrine sweat glands that are distributed throughout the body and are particularly numerous on the palms and soles of the hands, face, and armpits. The eccrine sweat glands are spiral and clustered glands that open directly onto the skin surface. They are innervated by cholinergic nerve fibers … Heavy Sweating
Products Tapentadol is approved in film-coated tablet, sustained-release tablet, and solution forms (Palexia /-retard). It was released in many countries in late February 2011 and went on sale in the fall. Tapentadol, like tramadol (Tramal, generics), was developed at Grünenthal. The sustained-release tablets were approved in 2013 and the solution went on sale in many … Tapentadol
Definition Medication overuse involves using self-purchased or physician-prescribed medications for too long, too much, or too frequently. The duration of therapy prescribed by a healthcare professional or by the professional and patient information is exceeded, the maximum single or daily dose is too high because of a dose increase, or the dosing interval is too … Medication Overuse
Background Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter biosynthesized from the amino acid tryptophan by decarboxylation and hydroxylation. It binds to seven different families of the serotonin receptor (5-HT1 to 5-HT7) and elicits central and peripheral effects that affect mood, behavior, sleep-wake cycle, thermoregulation, pain perception, appetite, vomiting, muscles, and nerves, among others. Serotonin is vasoconstrictive … Serotonin Syndrome: Causes and Treatment
What SSRI drugs are available? Among the SSRIs there are some commonly prescribed drugs. These include sertaline, paroxetine, fluoxetine and fluvoxamine. Fluoxetine and fluvoxamine, which are marketed as Fluctin® and Fevarin®, have strong side effects and are therefore rarely prescribed if at all possible. Sertalin has few side effects and a good therapeutic range. Sertaline … What SSRI drugs are available? | SSRI
Interactions with other active ingredients Tramadol is a drug for the treatment of moderately severe to severe pain. It belongs to the group of opioids and is only available on prescription, but is not covered by the narcotics law in Germany. Serious interactions can occur when tramadol and SSRI are taken simultaneously. An accumulation of … Interactions with other active ingredients | SSRI
Send SSRI Abrupt SSRIs are generally not recommended. The body is accustomed to a fairly constant serotonin level during the intake of SSRI. If a patient suddenly stops taking the drug, the serotonin level also drops very quickly. The reason for this is the short half-life of the medication. Half-life is the time it takes … Send SSRI | SSRI
Alternatives to SSRI Antidepressants can have serious side effects that require a change. In addition to SSRIs, the class of antidepressants includes the so-called tricyclic antidepressants. Active ingredients in this group include amitriptyline, imipramine, clomipramine and others. However, due to their numerous side effects, they are no longer considered the first choice in the treatment … Alternatives to SSRI | SSRI
What are SSRIs? SSRI stands for selective serotonin reuptake inhibitors. These are drugs that prevent the reuptake of serotonin. Serotonin is an endogenous carrier substance, which is produced from the amino acid tryptophan, mainly in the central nervous system and the gastrointestinal tract. Introduction As a transmitter, serotonin mediates important functions in the body. A … SSRI
How do SSRIs work? SSRIs exert their effect by inhibiting a serotonin transporter at the presynapse. Under normal circumstances, the serotonin from the synaptic cleft would be returned to the presynapses by this transporter, where it would be “packed” into small transport vesicles and released into the synaptic cleft again during a new synaptic transmission … How do SSRIs work? | SSRI
