Silymarin (Milk Thistle Fruit Extract): Safety Evaluation

No adverse effects have been reported in clinical intervention studies conducted to date. In animal studies, oral intake of a maximum of 2,500 to 5,000 mg/kg silymarin has been shown to be nontoxic and symptom-free. Caution should be exercised in cases of hypersensitivity to the active ingredient and other plants of the genus Asteraceae (or … Silymarin (Milk Thistle Fruit Extract): Safety Evaluation

Other Vital Substances

The following are active substances (micronutrients) that also perform important tasks in the body: In addition to macronutrients (carbohydrates, proteins, fats) and the well-known vital substances – vitamins, minerals, trace elements, essential fatty acids, essential amino acids, and bioactive substances – there are numerous compounds in foods that also perform important vitamin-like functions in the … Other Vital Substances

Silymarin (Milk Thistle Fruit Extract): Interactions

There are moderate interactions between silymarin and drugs that are metabolized (metabolized) in the liver via cytochromes P450 2C9. Concomitant use of silymarin and these drugs may slow their breakdown and increase their effects and side effects. Furthermore, there are interactions between milk thistle and glucuronidated drugs. In this case, the effect of the drugs … Silymarin (Milk Thistle Fruit Extract): Interactions

Winter Cherry (Withania Somnifera): Functions

In Ayurvedic medicine, the sleep berry is very often used due to its diverse effectiveness. Traditionally, mainly the leaves and roots of the medicinal plant are used with the aim of promoting calmness and clarity of mind, as well as rebalancing body and mind. According to this, the sleeping berry is said to have memory-enhancing, … Winter Cherry (Withania Somnifera): Functions