Brodifacoum

Products Brodifacoum is found in mouse and rat poisons. Structure and properties Brodifacoum (C31H23BrO3, Mr = 523.4 g/mol) is a brominated coumarin (4-hydroxycoumarin) and warfarin derivative. It was developed because resistance occurred with the use of warfarin. Brodifacoum exists as an off-white to beige powder that is sparingly soluble in water. The melting point is … Brodifacoum

Cranberry Effects, Adverse Effects and Dosage

Products Preparations made from cranberries are commercially available as juice, capsules, tablets, powder and tea, among others. Dried and sugared cranberries are also available. Stem plant The American cranberry (large-fruited cranberry) Aiton from the heather family is native to North America and is cultivated on a large scale. The European cranberry L. is less common … Cranberry Effects, Adverse Effects and Dosage

Ester

Definition Esters are organic compounds formed by the reaction of an alcohol or phenol and an acid such as a carboxylic acid. The condensation reaction releases a water molecule. The general formula of esters is: esters can also be formed with thiols (thioesters), with other organic acids, and with inorganic acids such as phosphoric acid … Ester

Goji

Products Goji berries and corresponding preparations such as capsules, juices or cosmetics are available from various suppliers, including pharmacies, drugstores and health food stores. Goji is an artificial word of recent origin, which is derived from the Chinese name. The berries belong to the so-called superfoods. Stem plants The berries come from two plants: Common … Goji

Ginseng Health Benefits

Products Preparations containing ginseng are commercially available in the form of capsules, juice, and lozenges, among others. Ginseng is included in registered drugs and in dietary supplements. In East Asia and Southeast Asia, ginseng has been used medicinally for thousands of years. Stem plant C.A. Meyer, of the Araliaceae family, is native to Manchuria in … Ginseng Health Benefits

Zafirlukast

Products Zafirlukast was commercially available in the form of film-coated tablets (Accolate, off label). It was approved in many countries in 1998. It was discontinued from distribution in 2019. Montelukast is a suitable substitute. Structure and properties Zafirlukast (C31H33N3O6S, Mr = 575.7 g/mol) exists as a fine, white to pale yellow, amorphous powder that is … Zafirlukast

Ivermectin

Products Ivermectin is commercially available in some countries in tablet form (Stromectol). It has not yet been registered in many countries and therefore must be imported from abroad if needed. Ivermectin has been used medicinally since the 1980s, initially primarily as a veterinary drug. This article refers to peroral administration in humans. See also under … Ivermectin

Difenacoum

Products Difenacoum is found in mouse and rat poisons (e.g., Gesal Protect rat and mouse bait). It has been available since the 1970s. Structure and properties Difenacoum is a (C31H24O3, Mr = 444.5 g/mol) is a 4-hydroxycoumarin, warfarin, and biphenyl derivative. It was developed to overcome resistance to warfarin (“superwarfarin”). Difenacoum is structurally closely related … Difenacoum

Phytomenadione

Products Phytomenadione is commercially available as a solution for injection and a solution for oral use (Konakion MM). It has been approved in many countries since 1987. Structure and properties Phytomenadione (C31H46O2, Mr = 450.7 g/mol) is a mixture of -phytomenadione, -phytomenadione, and -epoxyphytomenadione. It exists as a clear, intense yellow, viscous, oily liquid and … Phytomenadione

Warfarin: Effects, Uses & Risks

Warfarin is a medical agent with anticoagulant properties. Mainly in the USA, it is used for the treatment of thrombosis. In Europe, phenprocoumon, a drug of the same class of active ingredients, is mostly used for this purpose. What is warfarin? Warfarin is a medical agent with anticoagulant properties. It is used to treat thrombosis. … Warfarin: Effects, Uses & Risks

Distribution

Definition Distribution (distribution) is a pharmacokinetic process that begins immediately after absorption of the drug from the intestine. During this process, the drug enters the bloodstream and travels to organs, body fluids, and tissues. Distribution is necessary for the drug to reach its drug target at a sufficient concentration. For example, an antidepressant must be … Distribution

Rabeprazole

Products Rabeprazole is commercially available in the form of film-coated tablets (Pariet, generic). It has been approved in many countries since 1999. Generic versions have been available since 2012. Structure and properties Rabeprazole (C18H21N3O3S, Mr = 359.4 g/mol) is a benzimidazole and pyridine derivative and a racemate. It is present in drugs as rabeprazole sodium, … Rabeprazole